Left main coronary thrombosis with essential thrombocythemia

Abstract

Essential thrombocythemia is a disorder that causes persistent increase in the platelet count. The disease is associated with an elevated risk of thrombosis. A 71-year-old woman was diagnosed with left main coronary thrombosis after an angiogram due to stable angina. One week before the angiogram was taken the patient had also been diagnosed with essential thrombocythemia. After appropriate medical treatment for 5 days the patient underwent an excimer laser treatment, which failed in dissolving the thrombus. Before the patient underwent coronary surgery, thrombopheresis was performed in order to reduce the platelet count. After a successful coronary operation the patient improved completely.

Essential Thrombocythemia: A Case of Acute ST‐Segment Elevation Myocardial Infarction in a Young Female

“…We could find only 7 cases of MI in female patients with ET in the literature and the age of all these patients was older than our patient. 4,5 Similar to our patient, the LAD artery was occluded in most of the patients presented with MI and ET.…”

Development of acute myocardial infarction in a young female patient with essential thrombocythemia treated with anagrelide: a case report

“…If an effective cytoreductive therapy is not introduced, acute coronary syndromes resulting from coronary artery involvement may develop in patients with ET. However, case reports of MIs in well-controlled cases of ET are rare, and most reports are of elderly subjects with various cardiovascular risk factors [7, 10, 11]. Our patient was a young woman with no smoking history and without hypertension, dyslipidemia, diabetes mellitus, or obesity.…”

Left main coronary artery thrombosis revealing angio-Behçet syndrome

“…Given the marked thrombotic burden in the left main, anti-GpIIb–IIIa (tirofiban) was given. Similarly, other successful cases of fibrinolysis were reported [18] in addition to efficiency of anti-GpIIb–IIIa [19], which was, in preference, indicated in case of fresh thrombus floating in coronary arteries without delayed flow or need for emergent revascularization. Moreover, according to the case reported by Ergelen et al [20] illustrating left main thrombosis with stable hemodynamic status in a patient suffering from BD, successful fibrinolysis followed by the use of anti-GpIIb–IIIa had proved effective as demonstrated by further coronary angiography showing patent coronary arteries.…”