2020
DOI: 10.1007/s15010-020-01402-x
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Left-sided infective endocarditis in persons who inject drugs

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Cited by 6 publications
(3 citation statements)
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“…We found in this study that patients with right-sided valvular infection were predominant and mostly affected by Staphylococcus aureus , similar to prior study around the same time frame in North Carolina [ 3 ], with similar patterns of mitral valves being involved more than aortic valves. Patients with left-sided involvement in this study were found to have significantly more PFO.…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
“…We found in this study that patients with right-sided valvular infection were predominant and mostly affected by Staphylococcus aureus , similar to prior study around the same time frame in North Carolina [ 3 ], with similar patterns of mitral valves being involved more than aortic valves. Patients with left-sided involvement in this study were found to have significantly more PFO.…”
Section: Discussionsupporting
confidence: 89%
“…Infective material in the blood stream should be eliminated by the pulmonary macrophages and other immune systems, yet, left-sided IE (those involving mitral and/or aortic valves) is not uncommon. Previous research suggests that IVDU patients with left-sided IE tend to be younger, have more frequent multi-valve involvement, Staphylococcus aureus infections, previous IE, and experience more strokes [ 3 ]. This study was set out to see the common denominators for patients with left-sided IE, and hopefully help clinicians identify potential risk factors for IVDU patients to develop left-sided and/or mixed (right and left), as opposed to right-sided IE.…”
Section: Introductionmentioning
confidence: 99%
“…Unlike IE seen decades ago, more rural areas have described escalating rates of IE among younger, otherwise healthy people who inject drugs (PWID), with a predominance of infection due to Staphylococcus aureus , one of the most virulent pathogens that causes IE [ 6 ]. Moreover, IDU-related IE has not been limited to right-sided IE, as both left-sided and bilateral involvement have often been seen with increased morbidity and mortality [ 7 ]. Despite the prevalence of PWID/IE in some rural areas, larger tertiary care centers in urban environments have also been impacted, in part related to the referral of IE patients for management expertise.…”
mentioning
confidence: 99%