Left ventricular blood flow patterns in normal subjects: A quantitative analysis by three-dimensional magnetic resonance velocity mapping

Kim, Won Yong; Walker, Peter G.; Pedersen, Erik Morre; Poulsen, Jakob Lykke; Oyre, Sten; Houlind, Kim Christian; Yoganathan, Ajit P.

doi:10.1016/0735-1097(95)00141-l

Cited by 238 publications

(194 citation statements)

References 20 publications

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“…The videos were systematically reviewed frame by frame and the resulting flows were examined to testify the reduction of vortex penetration in the LV with the increase of infarct size. In vivo visualization of the actual LV vortex pattern in normal subjects were first recorded by CMR, 54 and the asymmetric sinuous flow paths around the vortex in the human heart were elegantly described shortly after. 51 It was suggested that the asymmetric vortical arrangement is the fluid functional counterpart of the looped heart structure, which enhances the atrio-ventricular mechanical synergy and supports the conservation of momentum from the entry jet to the ejected flow.…”

Section: First Studies On Vortex Formationmentioning

confidence: 99%

Left Ventricular Fluid Mechanics: The Long Way from Theoretical Models to Clinical Applications

Pedrizzetti

Domenichini

2014

Ann Biomed Eng

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Abstract-The flow inside the left ventricle is characterized by the formation of vortices that smoothly accompany blood from the mitral inlet to the aortic outlet. Computational fluid dynamics permitted to shed some light on the fundamental processes involved with vortex motion. More recently, patient-specific numerical simulations are becoming an increasingly feasible tool that can be integrated with the developing imaging technologies. The existing computational methods are reviewed in the perspective of their potential role as a novel aid for advanced clinical analysis. The current results obtained by simulation methods either alone or in combination with medical imaging are summarized. Open problems are highlighted and perspective clinical applications are discussed.

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Section: First Studies On Vortex Formationmentioning

confidence: 99%

Left Ventricular Fluid Mechanics: The Long Way from Theoretical Models to Clinical Applications

Pedrizzetti

Domenichini

2014

Ann Biomed Eng

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“…Initially, the term three-dimensional was used to describe a three-directional twodimensional MRI acquisition (29). Later on, 3D cine PC MRI acquisitions have sometimes being referred to as 4D or 7D.…”

Section: Three-dimensional Cine Phase-contrast Mri Acquisitionmentioning

confidence: 99%

Flow Imaging: Cardiac Applications of 3D Cine Phase-Contrast MRI

Ebbers

2011

Curr Cardiovasc Imaging Rep

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Global and regional blood flow dynamics are of pivotal importance to cardiac function. Fluid mechanical forces can affect hemolysis and platelet aggregation, as well as myocardial remodeling. In recent years, assessment of blood flow patterns based on time-resolved, three-dimensional, three-directional phasecontrast magnetic resonance imaging (3D cine PC MRI)(1) has become possible and rapidly gained popularity. Initially, this technique was mainly known for its intuitive and appealing visualizations of the cardiovascular blood flow. Most recently, the technique has begun to go beyond compelling images towards comprehensive and quantitative assessment of blood flow. In this article, cardiac applications of 3D cine PC MRI data are discussed, starting with a review of the acquisition and analysis techniques, and including descriptions of promising applications of cardiac 3D cine PC MRI for the clinical evaluation of myocardial, valvular and vascular disorders.3

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“…The numerical scheme of this restoration method [6] can be defined as follows. Firstly, the strength function e(u; ) at voxel can be defined as: (1) where N α denotes the neighbourhood of pixel α and d l denotes the embedded Euclidean distance in S 2 . The TV-energy of the direction field in domain Ω is then: (2) and the constrained optimisation can be written as:…”

Section: Flow Field Restorationmentioning

confidence: 99%

“…In particular, vortical motion, known to exist in the diastolic phase of the cardiac cycle [1], is the most important flow feature and its evolution over different phases of the cardiac cycle can provide important insight into the health status of the heart. Previous research [2] has shown that in order to achieve a comprehensive and integrated description of flow in health and disease, it is necessary to characterise and model both normal and abnormal flows and their effects.…”

Section: Introductionmentioning

confidence: 99%

Flow Field Abstraction and Vortex Detection for MR Velocity Mapping

Carmo

Yang

2003

Lecture Notes in Computer Science

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Abstract. The evolution of blood flow patterns (vortical flow features in particular) and their interactions with cardiovascular structure is important in the study of cardiovascular function. The winding index method is widely used for vortex detection and has shown to be very sensitive to noise. We propose a novel technique for the detection of vortical flow features that consists of three main components: flow restoration, abstraction and vortex detection. Firstly, an abstract flow field is obtained by clustering the flow field restored using our proposed restoration method. Afterwards, critical points are computed from the abstract flow field and then phase portrait theory is employed to identify vortices. The proposed technique is applied to 12 sets of MR velocity maps acquired from patients with sequential MR examination following myocardial infarction and the results show that vortical flow patterns are more readily detected compared to the winding index method.

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Left ventricular blood flow patterns in normal subjects: A quantitative analysis by three-dimensional magnetic resonance velocity mapping

Abstract: The hypothesis of a diastolic vortex formation in the human left ventricle was confirmed, and its close temporal relation to the motion of the anterior mitral leaflet was demonstrated.

Cited by 238 publications

References 20 publications

Left Ventricular Fluid Mechanics: The Long Way from Theoretical Models to Clinical Applications

Left Ventricular Fluid Mechanics: The Long Way from Theoretical Models to Clinical Applications

Flow Imaging: Cardiac Applications of 3D Cine Phase-Contrast MRI

Flow Field Abstraction and Vortex Detection for MR Velocity Mapping

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