Left Ventricular Function in Mitral Stenosis

Horwitz, Lawrence D.; Mullins, C. Buddie; Payne, Robert M.; Curry, George C.

doi:10.1378/chest.64.5.609

Cited by 54 publications

(17 citation statements)

References 18 publications

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“…In these patients, however, the EDV is either normal or augmented [1,5,12,24], The decreased SV/EDV in our patients with mitral stenosis sug gests the presence of yet another factor, i.e. the deterioration of myo cardial performance which has been demonstrated angiocardiographically [13][14][15].…”

Section: Discussionsupporting

confidence: 47%

Left Ventricular End-Diastolic Volume in Advanced Ischemic Heart Disease; Comparison between Healthy Subjects and Patients with Mitral Stenosis

Kasalický¹,

Fabián²,

Ressl³

et al. 1975

Cardiology

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The left ventricular end-diastolic volume (EDV), end-systolic volume (ESV) and systolic ejection fraction (SV/EDV) were determined in 6 healthy subjects, 21 patients with ischemic heart disease and 8 patients with mitral stenosis by the left ventricular ¹³³Xe washout technique. Cardiac and stroke indexes as well as left ventricular work and stroke work indexes do not differ in all three groups. A significantly higher EDV and ESV together with a low SV/EDV suggested impaired left ventricular function in patients with ischemic heart disease.

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Section: Discussionsupporting

confidence: 47%

Left Ventricular End-Diastolic Volume in Advanced Ischemic Heart Disease; Comparison between Healthy Subjects and Patients with Mitral Stenosis

Kasalický¹,

Fabián²,

Ressl³

et al. 1975

Cardiology

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“…the supposition is certainly reasonable considering anatomical findings (Grant, 1953;Horwitz et al, 1973) or echocardiographic data which showed that fibrosis or calcification frequently extended to the posterior ventricular wall (D'Cruz et al, 1979).…”

Section: Discussionmentioning

confidence: 79%

Global left ventricular function and regional wall motion in pure mitral stenosis‐Left ventricular function in pure mitral stenosis

Colle

Rahal

Ohayon

et al. 1984

Clinical Cardiology

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Summary:Global left ventricular function (LVF) and segmental wall motion of the left ventricle are registered in 113 patients presenting a pure mitral stenosis (MS) and in a control group of 50 individuals. The segmental wall motion is measured on the end-diastolic-end-systolic frames of the left ventricle, obtained from right anterior oblique (RAO) monoplane cineangiography . Measurement of the segmental wall shortening is performed using the Stanford method. Group 1 includes 68 patients (60% of the total number of patients studied). These patients show no pathological contraction abnormality. In this group, the global LVF is not different from the control group. Group 2 includes 45 patients (40% of the total) for whom contraction abnormalities are present: anterior hypokinesis in 20% of the cases (anterior area mean shortening (AAS) = 18f8%; p

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“…Both groups had mildly reduced left ventricular enddiastolic volume index, an observation that has been previously made in patients with severe MS, 17 whereas an increased end-diastolic volume has been reported after successful PBMV. 19 Several mechanisms have been suggested to explain the reduced LVEF in patients with severe MS: (1) reduced preload or impaired diastolic ®lling 3,20 ; (2) depressed left ventricular contractile function 5,21 ; and (3) increased systemic afterload. 22 Rayburn and Fortuin 7 studied a group of patients with MS and low gradient and found a higher incidence of subvalvar mitral disease in this unique group of patients.…”

Section: Hemodynamic Characteristicsmentioning

confidence: 99%

Percutaneous balloon mitral valvuloplasty in patients with severe mitral stenosis and low transmitral diastolic pressure gradient

Turgeman

Atar

Suleiman

et al. 2003

International Journal of Cardiovascular Interventions

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An elevated left atrial pressure and high diastolic pressure gradient (DPG) across the mitral valve are the major hemodynamic abnormalities in mitral stenosis (MS). However, a subgroup of patients with severe MS is characterized by low initial DPG. The authors reviewed the clinical, echocardiographic and hemodynamic data as well as procedural results in 180 patients who underwent percutaneous balloon mitral valvuloplasty (PBMV). An initial mean DPG > 10 mmHg was found in 144 patients (80%) (group A) and mean DPG < or = 10 mmHg in 36 patients (20%) (group B). Patients in group A had higher left ventricular ejection fraction (LVEF) than in group B (61 +/- 5% versus 42 +/- 6%, respectively) and higher cardiac index (2.8 +/- 0.4 versus 2.0 +/- 0.3 l/min/m(2) ). In group B 12 patients (33%) had normal LVEF, whereas 24/36 (67%) had reduced LVEF. All the latter had wall motion abnormalities on ventriculography. Unlike group A, intraprocedural echocardiography was essential for monitoring and evaluating immediate results of PBMV in group B. On follow-up of three years, 75% of group A patients and 55% in group B were in functional class I (p < 0.05). PBMV did not significantly improve symptoms in patients in group B who had preprocedure LVEF < or = 35%.

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Left Ventricular Function in Mitral Stenosis

Cited by 54 publications

References 18 publications

Left Ventricular End-Diastolic Volume in Advanced Ischemic Heart Disease; Comparison between Healthy Subjects and Patients with Mitral Stenosis

Left Ventricular End-Diastolic Volume in Advanced Ischemic Heart Disease; Comparison between Healthy Subjects and Patients with Mitral Stenosis

Global left ventricular function and regional wall motion in pure mitral stenosis‐Left ventricular function in pure mitral stenosis

Percutaneous balloon mitral valvuloplasty in patients with severe mitral stenosis and low transmitral diastolic pressure gradient

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