Left Ventricular Hemodynamic Changes and Clinical Outcomes after Transcatheter Atrial Septal Defect Closure in Adults

Ermis, Peter; Franklin, Wayne; Mulukutla, Venkatachalam; Parekh, Dhaval R.; Ing, Frank F.

doi:10.1111/chd.12204

Cited by 14 publications

(9 citation statements)

References 34 publications

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“…In our study, we provided the complete three years follow-up transthoracic echocardiographic data of part of cases. The postoperative data showed significantly improved heart structure and function compared with the preoperative data, which was mentioned in our previous report and is similar to others’ results [ 32 , 33 ]. These were mainly because the left to right shunt was blocked, the right heart volume and pressure load rapidly decreased, and the load of left heart system capacity increased correspondingly.…”

Section: Discussionsupporting

confidence: 91%

“…The corresponding changes also occurred in the left atrium and ventricle. As our data showed, RV-FAC and RV-Tei index had reduced and LV-EF had increased, which meant the cardiac function was significantly improved and could reach a new equilibrium after a period of recovery time [ 32 , 33 ]. These were justified on the grounds that ASD closure with the large device also avoided long term heart dysfunction.…”

Section: Discussionmentioning

confidence: 99%

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Midterm follow-up of transthoracic device closure of an atrial septal defect using the very large domestic occluder (44–48 mm), a single Chinese cardiac center experience

Chen

Cao

Zhang

et al. 2017

J Cardiothorac Surg

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BackgroundThe purpose of this study was to outline the midterm follow-up results and complications in patients who underwent transthoracic device closure of an atrial septal defect (ASD) with the very large domestic occluder (44–48 mm).MethodsThe data of 35 patients who underwent transthoracic device closure of an ASD with the very large domestic occluder (44–48 mm) at our institution were collected prospectively between January 2010 and January 2015. All patients were invited for an outpatient visit and contrast TTE for 12–70 months after ASD closure.ResultsThirty-four patients were occluded successfully under this approach and 1 patient was transferred for surgical repair for dislodgement of the occluder. The most frequent complication was transient cardiac arrhythmia. A new third degree atrioventricular block occurred in 1 patient who recovered 1 week later. During the follow-up period, we found no recurrence, no thrombosis, no device embolization, no device failure, and no cases of death. The total occlusion rate was 94.1% in the 12 months of follow-up, and the intracardiac structure and cardiac function were significant improved contemporaneously.ConclusionTransthoracic device closure of an atrial septal defect with the very large domestic occluder (44–48 mm) is a safe and feasible technique. However, long-term follow-up is required to better assess the safety and feasibility of this method for the closure of very large ASDs in patients.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Midterm follow-up of transthoracic device closure of an atrial septal defect using the very large domestic occluder (44–48 mm), a single Chinese cardiac center experience

Chen

Cao

Zhang

et al. 2017

J Cardiothorac Surg

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“…The indication for ASD closure has been shown as a significant result in a decrease in symptoms and improvement of exercise [8,9]. First introduced by Mills and King [10] in 1976, ASD has transitioned from surgical techniques to transcatheter base approaches using a variety of occlusion devices [11]. Amplatzer® septal occluder (St. Jude Medical, St. Paul, MN, USA) is the most commonly used device for ASD closure [10].…”

Section: Introductionmentioning

confidence: 99%

Left Ventricular Torsion Deformation in Atrial Septal Defect Patients Undergoing Transcatheter Device Closure

Razak

Hajri

Shetty

et al. 2018

ijcp

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Introduction: Atrial septal defects (ASD) considered being one of the known congenital heart diseases. ASD causes increased volume overload of the right heart. The purpose of this study was to evaluate left ventricular (LV) torsion deformation in ASD patients undergoing transcatheter device closure. Methods: All adult patients who underwent transcatheter device closure with ostium secundum ASD were included in the study. We assessed LV torsion in ostium secundum ASD patient's pre and post device closure by using speckle tracking echocardiography. Results: A total of 37 patients (22 females and 15 males) were included in this study. The average age was 28 ± 19 years. LV peak basal rotation improved significantly (P = 0.028) in post transcatheter closure. LV torsion (2.88 ± 0.99˚/cm before vs. 3.40 ± 1.41˚/cm after closure, P = 0.009) and twisting (15.12 ± 4.69˚ before vs. 17.95 ± 6.21˚ after closure, P = 0.005) were statistically significant in post transcatheter closure. Volumetric assessment of LV including end-diastolic volume and systolic volume showed significant improvement (P = 0.02, P < 0.01) post device closure. Conclusions: The increased peak LV twisting and torsion was mainly attributed to the improved peak systolic clockwise rotation after ASD device closure. The LV twisting at a younger age was improved after the closure of ASD.

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“…3 It has been demonstrated that device closure of ASDs lead to an improvement in right and left heart volumes as a result of removal of left-to-right shunt. 4,5 Furthermore, cardiac remodeling occurs quite quickly after ASD device closure and continues for at least 1 year, which causes amelioration in cardiac functions. 6 The myocardial performance index (MPI) obtained by tissue Doppler echocardiography (TDE) has been widely used to quantitatively assess myocardial performance.…”

Section: Introductionmentioning

confidence: 99%

Both Systemic and Pulmonary Artery Stiffness Predict Ventricular Functional Recovery after Successful Percutaneous Closure of Atrial Septal Defects in Adults

Baykan

Gür

Acele

et al. 2015

Congenital Heart Disease

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Left Ventricular Hemodynamic Changes and Clinical Outcomes after Transcatheter Atrial Septal Defect Closure in Adults

Abstract: Percutaneous ASD closure induces an increase in LVEDP. Despite this, all patients tolerated device closure without complication. It appears safe to close ASDs in these patients.

Cited by 14 publications

References 34 publications

Midterm follow-up of transthoracic device closure of an atrial septal defect using the very large domestic occluder (44–48 mm), a single Chinese cardiac center experience

Midterm follow-up of transthoracic device closure of an atrial septal defect using the very large domestic occluder (44–48 mm), a single Chinese cardiac center experience

Left Ventricular Torsion Deformation in Atrial Septal Defect Patients Undergoing Transcatheter Device Closure

Both Systemic and Pulmonary Artery Stiffness Predict Ventricular Functional Recovery after Successful Percutaneous Closure of Atrial Septal Defects in Adults

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