Left Ventricular Reconstruction Brings Benefit for Patients With Ischemic Cardiomyopathy

Ribeiro, Gustavo C. A.; Antoniali, Fernando; Lopes, Melina Savioli; Costa, Cledicyon Eloy da; Albuquerque, Ana Nunes; Franchini, Kleber G.

doi:10.1016/j.cardfail.2005.11.002

Cited by 15 publications

(6 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Regarding surgical LV reconstruction, preliminary data from registries and one small prospective randomized study demonstrated favorable outcomes in surgical LV aneurysmectomy, generally with concomitant coronary artery bypass grafting (CABG), on ventricular volume reduction, functional status, ischemic mitral regurgitation, and HF hospitalization burden [8][9][10][11]. Aguiar Ribeiro et al demonstrated the benefit of LV reconstruction in addition to CABG in patients with ischemic cardiomyopathy in a small prospective randomized controlled singlecenter trial (n = 74) [11]. NYHA class significantly improved and the incidence of HF recurrences and rehospitalizations was lower in the LV reconstruction arm.…”

Section: Discussionmentioning

confidence: 99%

“…LV reconstruction in ischemic cardiomyopathy has generally been performed in the setting of standard open-heart surgery, where aneurysm resection is usually accompanied by other interventions, mostly coronary artery revascularization [8][9][10][11][12]. Hybrid transcatheter and minithoracotomy LV reconstruction represents a novel treatment option for this cohort of patients with favorable safety and efficacy short-term results [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy

Naar

Skalský

Krüger

et al. 2021

J. of Cardiovasc. Trans. Res.

View full text Add to dashboard Cite

The evidence supporting surgical aneurysmectomy in ischemic heart failure is inconsistent. The aim of the study was to describe long-term effect of minimally invasive hybrid transcatheter and minithoracotomy left ventricular (LV) reconstruction in patients with ischemic cardiomyopathy. Twenty-three subjects with transmural anterior wall scarring, LV ejection fraction 15–45%, and New York Heart Association class ≥ II were intervened using Revivent TC anchoring system. LV end-systolic volume index was reduced from 73.2 ± 27 ml at baseline to 51.5 ± 22 ml after 6 months (p < 0.001), 49.9 ± 20 ml after 2 years (p < 0.001), and 56.1 ± 16 ml after 5 years (p = 0.047). NYHA class improved significantly at 5 years compared to baseline. Six-min walk test distance increased at 2 years compared to the 6-month visit. Hybrid LV reconstruction using the anchoring system provides significant and durable LV volume reduction during 5-year follow-up in preselected patients with ischemic heart failure. Graphical abstract

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy

Naar

Skalský

Krüger

et al. 2021

J. of Cardiovasc. Trans. Res.

View full text Add to dashboard Cite

show abstract

“…2, 3 However, the NIH-sponsored Surgical Treatment for Ischemic Heart failure (STICH) trial recently found no difference in composite outcome between coronary bypass (CABG) and CABG plus Dor procedure. 4 The authors speculated that improved systolic function was balanced by worsened diastolic function.…”

Section: Introductionmentioning

confidence: 99%

Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zone

Sun

Suzuki

Wenk

et al. 2010

The Journal of Thoracic and Cardiovascular Surgery

View full text Add to dashboard Cite

Background Endoventricular patch plasty (Dor) is used to reduce left ventricular (LV) volume after myocardial infarction (MI) and subsequent LV remodeling. Methods and Results End-diastolic and end-systolic pressure volume and Starling relationships were measured and magnetic resonance (MRI) images with non-invasive tags used to calculate 3D myocardial strain in six sheep 2 weeks before, and 2 and 6 weeks after the Dor procedure. These experimental results were previously reported. The imaging data from one sheep was incomplete. Animal specific finite element (FE) models were created from the remaining five animals using MRI images and LV pressure obtained at early diastolic filling. FE models were optimized using 3D strain and used to determine systolic material properties, Tmax,skinned-fiber, and diastolic and systolic stress in remote myocardium and borderzone (BZ). Six weeks after Dor procedure, end-diastolic and end-systolic stress in the BZ were substantially reduced. However, although there was a slight increase in Tmax,skinned-fiber in the BZ near the MI at 6 weeks, the change was not significant. Conclusions The Dor procedure decreases end-diastolic and end-systolic stress but fails to improve contractility in the infarct BZ. Future work should focus on measures that will enhance BZ function alone or in combination with surgical remodeling.

show abstract

“…48,49 Altogether, 237 papers were identifi ed on the subject, with 15 presenting the best evidence to answer this clinical question. 42,[50][51][52][53][54][55][56][57][58] The RESTORE group and others have demonstrated that in patients with ICM and an akinetic anterior ventricular wall signifi cantly improved survival and symptom alleviation can be obtained with an acceptable operative risk. Improvement in the ejection fraction of 10%-15% have been consistently demonstrated with signifi cant alleviation of symptoms.…”

Section: Effectiveness Of Svr and Stich Trialmentioning

confidence: 99%

Surgical left ventricular reconstruction

Isomura¹

2011

Gen Thorac Cardiovasc Surg

View full text Add to dashboard Cite

Because of the shortage of donors for heart transplantation, surgical ventricular reconstruction (SVR) has been under development to treat end-stage heart failure due to a dilated left ventricle. The operative procedures have been developed and modified based on the clinical results and preoperative findings of several examinations. SVR is performed to reduce the size and volume of the ventricle as well as to reshape it. The procedures, which differ based on the particular left ventricular lesion, are endoventricular patch plasty or septal anterior ventricular restoration for anteroseptal exclusion and partial left ventriculectomy or a posterior restoration procedure for posterolateral exclusion. In the indicated patients, SVR has been emerging as an alternative to heart transplantation. The accumulating surgical knowledge may provide new opportunities for the treatment of ischemic dilated cardiomyopathy. The Surgical Treatment for Ischemic Heart Failure (STICH) trial seems to have arrived at a misguided conclusion. Surgeons have to know not only the operative procedures for SVR; they must also be aware of the systolic and diastolic functioning and the volume and size of the left ventricle before and after SVR. Hence, SVR is reviewed and discussed here.

show abstract

Left Ventricular Reconstruction Brings Benefit for Patients With Ischemic Cardiomyopathy

Cited by 15 publications

References 17 publications

Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy

Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy

Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zone

Surgical left ventricular reconstruction

Contact Info

Product

Resources

About