Left ventricular stiffness assessed by diastolic Wall strain predicts asymptomatic atrial high-rate episodes in patients with pacemaker implantation

Can we explore AF–pacemakers’ relationship using clinical and echocardiographic parameters in patients with permanent pacemaker? (Echocardiography and subclinical AF in permanent pacemaker)

“…In this study we found an increase in the LV stiffness assessed by lower DWS and higher LV stiffness index in AF group, in agreement with many studies [14,[19][20][21][22]; the DWS at a cut off value < 0.34 had a sensitivity of 80.5%, a specificity of 75.6%, NPV of 86.8%, PPV of 66% and an accuracy of 77.4% (AU = 0.79, p < 0.001) and the LV stiffness index at a cut off value > 0.13 had a sensitivity of 61.1%, a specificity of 78.6%, NPV of 77.4%, PPV of 62.7% and an accuracy of 69.95% (AUC = 0.78, p < 0.001) in prediction of AF among the studied cases, with significant + ve correlation of the LV stiffness index and other parameters of LV diastolic dysfunction as older age, LAVI and more P wave dispersion, all these parameters were more prominent in AF group, in agreement with Antoni et al [23], Dilaveris and Gialafos [24] and Lopes RD, et al [25], while the DWs had significant-ve correlation with LAVI, P wave dispersion and DWS.…”

“…Other parameters of LV diastolic dysfunction as E/é ratio was higher in the AF group in our study in agreement with H. Kishima et al [21].…”

New-onset atrial high-rate episodes in left bundle branch area pacing versus right ventricular pacing for patients with atrioventricular block

“…In 2020, Witt et al [16] found that left atrial emptying fraction and left atrial minimum volumes (LAmin) assessed by cardiac computed tomography were significantly associated with AHREs (HR, 0.95; 95% CI, 0.92-0.98, and HR, 1.02; 95% CI, 1.00-1.05). In the same year, Kishima et al [17] found left ventricular stiffness assessed by diastolic wall strain was associated with AHREs in patients with a dual-chamber pacemaker. They speculated that increased left ventricular stiffness augmented left ventricular filling pressure, and further led to left atrial remodeling, which may then induce AHREs.…”

New-Onset Atrial High-Rate Episodes in Left Bundle Branch Area Pacing Versus Right Ventricular Pacing for Patients With Atrioventricular Block

“…In 2020, Witt et al[16] found that left atrial emptying fraction (LAEF) and left atrial minimum volumes (LA min ) assessed by cardiac computed tomography (CT) were signi cantly associated with AHREs (HR 0.95; 95%CI 0.92-0.98, and HR 1.02; 95%CI 1.00-1.05). In the same year, Kishima et al [17] found left ventricular stiffness assessed by diastolic wall strain (DWS) was associated with AHREs in patients with a duan-chamber pacemaker.…”