Left Ventricular Thickness Is Increased in Nonhypertensive Turner's Syndrome

Abstract

HR, LV wall thicknesses, LVMI and the LADi are significantly increased in normohypertensive TS women. There is also subclinical diastolic dysfunction in these patients.

Doppler‐Derived Strain Imaging Detects Left Ventricular Systolic Dysfunction in Children with Turner Syndrome

“…Previous study showed that LVMI was >95 g/m 2 in 32.2% of TS patients and in 3.3% of the control group . In accordance with previous study, LVMI of TS patients (66.3 ± 9.94) were significantly higher than those of controls (54.14 ± 6.92).…”

“…Previous studies concerning LV diastolic function in TS reported similar results in Doppler echocardiographic studies attributed to LV diastolic dysfunction . Another study showed that E/A ratio was <1 in 6.45% of TS patients and in 3.3% of control group . The presence of diastolic dysfunction in a group of children with no predisposing conditions is remarkable and may represent a syndromic trait in Turner's patients.…”

Left Ventricular Hypertrophy in Turner Syndrome: A Prospective Echocardiographic Study

“…The addition of a left ventricular mass estimate to conventional risk assessment improves prognostication in the general population 7 . This may also be the case for TS, where an abnormal left ventricular phenotype of unresolved etiology is a cardinal trait 8–10 . The left ventricle characteristically appears hypertrophied with subclinical diastolic and systolic dysfunction, and left atrial enlargement may be present 8–10 .…”

“…7 This may also be the case for TS, where an abnormal left ventricular phenotype of unresolved etiology is a cardinal trait. [8][9][10] The left ventricle characteristically appears hypertrophied with subclinical diastolic and systolic dysfunction, and left atrial enlargement may be present. [8][9][10] Current etiological understanding of left ventricular abnormalities in TS is limited.…”

“…[8][9][10] The left ventricle characteristically appears hypertrophied with subclinical diastolic and systolic dysfunction, and left atrial enlargement may be present. [8][9][10] Current etiological understanding of left ventricular abnormalities in TS is limited. However, the deviant cardiac appearances are likely to result from of a concert of causative mechanisms that may include frequently occurring bicuspid aortic valve, 11 aortic valve dysfunction, 12 coarctation of the aorta, 13 hypertension, 14 and endocrine and metabolic disorders.…”