Left Αtrial Remodeling in Patients Younger than 70 Years with Diastolic and Systolic Heart Failure

Left Atrial Remodeling and Function in Advanced Heart Failure With Preserved or Reduced Ejection Fraction

“…6,30,31 In an echocardiographic study, Triposkiadis et al compared LA remodeling in HFpEF and HFrEF and found more eccentric LA remodeling in HFrEF group, similarly to the current data. 31 In a smaller sample, Kurt et al reported that HFpEF patients had LA enlargement, reduced LA function, and increased LA stiffness compared with controls, but in contrast to the current study, LA stiffness was not as high in HFpEF as in HFrEF.…”

“…6,30,31 In an echocardiographic study, Triposkiadis et al compared LA remodeling in HFpEF and HFrEF and found more eccentric LA remodeling in HFrEF group, similarly to the current data. 31 In a smaller sample, Kurt et al reported that HFpEF patients had LA enlargement, reduced LA function, and increased LA stiffness compared with controls, but in contrast to the current study, LA stiffness was not as high in HFpEF as in HFrEF. 30 However, the Kurt study measured only mean PAWP rather than peak and minimal LA pressures, and the authors estimated LA stiffness simply as the ratio of mean PAWP to LA systolic strain, in contrast to the more robust methods used in the current study incorporating maximal and minimal LA pressure-volume coordinates.…”

Assessment of left atrial volume and mechanical function in ischemic heart disease

“…Several studies have demonstrated that the maximal LA volume assessed with two-dimensional echocardiography contains considerable prognostic information in population based studies as well as in patients with heart failure and acute myocardial infarction (MI) [3][4][5]. However, only few studies have investigated the detailed mechanical function of the LA and its relation to LV systolic function and clinical signs of heart failure in such patients [6][7][8][9].…”

Differential Left Atrial Remodeling in LV Diastolic Dysfunction and Mitral Regurgitation

“…LA size is also associated with the new development of HF and it plays an important role in HF, with or without a decreased LV ejection fraction 21 . LA remodeling is more severe in systolic HF than diastolic HF and it is governed by different mechanisms 22 . An enlarged LA can be remodeled according two different geometric patterns; determined by chronic pressure overload or volume overload.…”