Leg pain following<i>Staphylococcus aureus</i>bacteraemia

Mehmood, Mansoor; Bradford, Ako D; Khasawneh, Faisal A

doi:10.1136/bcr-2014-204603

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2020

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“…TP usually affects patients with a haematological disorder or malignancy [5], but can also occur in otherwise healthy individuals often secondary to (sometimes asymptomatic) bacteraemia or blunt trauma (usually a week before the onset of symptoms) [6,7]. Early diagnosis of TP is often missed because of its non‐specific presentation.…”

Section: Introductionmentioning

confidence: 99%

Tropical pyomyositis: an update

Shittu

Deinhardt‐Emmer

Nunes

et al. 2020

Tropical Med Int Health

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Tropical pyomyositis (TP) is a life-threatening bacterial infection of the skeletal muscle that occurs particularly among children, young adults and those with immunocompromised conditions. The appropriate diagnosis and treatment are often delayed due to its non-specific signs, leading to fatal consequences. Staphylococcus aureus, especially methicillin-susceptible S. aureus, is responsible for most TP cases. However, other bacteria (i.e. streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp., Candida spp., Mycobacterium spp.) have been reported. This narrative review provides an update on the epidemiology and clinical course of TP. A special focus is laid on the role of toxins (i.e. Panton-Valentine Leucocidin and a-toxin) in the pathogenesis of TP and their implication for the clinical management of infection.

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Section: Introductionmentioning

confidence: 99%