Legionella pneumonia in transplant recipients: a cluster of cases of eight years' duration

Prodinger, Wolfgang M.; Bonatti, Hugo; Allerberger, Franz; Wewalka, G.; Harrison, Tim; Aichberger, C.; Dierich, Manfred P.; Margreiter, R; Tiefenbrunner, F.

doi:10.1016/0195-6701(94)90042-6

Cited by 42 publications

(17 citation statements)

References 26 publications

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“…Legionella species, especially L. pneumophila , may be acquired from community or hospital sources; L. pneumophila is common in institutions with environmental colonization of water supplies 39, 50. The source may not be readily identified without the use of specific media51 and urine antigen tests during the routine work‐up of patients with pneumonia 39.…”

Section: Bacterial Infectionsmentioning

confidence: 99%

Bacterial, mycobacterial, and protozoal infections after liver transplantation—Part I

2005

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Section: Bacterial Infectionsmentioning

confidence: 99%

Bacterial, mycobacterial, and protozoal infections after liver transplantation—Part I

2005

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“…The problem of long-term colonization in anthropogenic water systems has arisen many times in environmental assessments, retrospective studies (183,(562)(563)(564)(565), and outbreak investigations (75,92,530,(566)(567)(568)(569)(570)(571). As illustrated in one recent outbreak report (75), ϳ35 cases of LD in condominium residents were discovered over 9 years due to the mistaken belief that low-level potable water contamination did not pose a significant disease threat; seemingly arbitrary "action levels" for remediation laid out by facility managers and defined by bacterial concentration thresholds resulted in recurrent and prolonged transmission and disease.…”

Section: Legionella Persistence and Remediationmentioning

confidence: 99%

Current and Emerging Legionella Diagnostics for Laboratory and Outbreak Investigations

2015

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SUMMARY Legionnaires' disease (LD) is an often severe and potentially fatal form of bacterial pneumonia caused by an extensive list of Legionella species. These ubiquitous freshwater and soil inhabitants cause human respiratory disease when amplified in man-made water or cooling systems and their aerosols expose a susceptible population. Treatment of sporadic cases and rapid control of LD outbreaks benefit from swift diagnosis in concert with discriminatory bacterial typing for immediate epidemiological responses. Traditional culture and serology were instrumental in describing disease incidence early in its history; currently, diagnosis of LD relies almost solely on the urinary antigen test, which captures only the dominant species and serogroup, Legionella pneumophila serogroup 1 (Lp1). This has created a diagnostic “blind spot” for LD caused by non-Lp1 strains. This review focuses on historic, current, and emerging technologies that hold promise for increasing LD diagnostic efficiency and detection rates as part of a coherent testing regimen. The importance of cooperation between epidemiologists and laboratorians for a rapid outbreak response is also illustrated in field investigations conducted by the CDC with state and local authorities. Finally, challenges facing health care professionals, building managers, and the public health community in combating LD are highlighted, and potential solutions are discussed.

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“…& al., 1994;Ezzeddine H. & al., 1989 ;Muraca P.W. & al., 1988;Prodinger W.M., 1994;Schultze-Robbecke R., 1990]. …”

Section: Comment Remédier à Ces Risques Potentiels ?unclassified

De l'importance de la prévention des maladies nosocomiales principalement d'origine hydrique en hygiène hospitalière

psychanalyste

Lafontaine

1998

Eur. j. water qual.

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Legionella pneumonia in transplant recipients: a cluster of cases of eight years' duration

Cited by 42 publications

References 26 publications

Bacterial, mycobacterial, and protozoal infections after liver transplantation—Part I

Bacterial, mycobacterial, and protozoal infections after liver transplantation—Part I

Current and Emerging Legionella Diagnostics for Laboratory and Outbreak Investigations

De l'importance de la prévention des maladies nosocomiales principalement d'origine hydrique en hygiène hospitalière

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