Legionnaires' Disease—The Benidorm Episode

Jh, Lawson

doi:10.1177/003693307802300204

Cited by 25 publications

(7 citation statements)

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“…A detailed clinical report about patients 3 and 4 has been prepared (Lawson, 1978). The five patients had been ill for 8, 8, 13, 10, and 8 days, respectively, and had received variable amounts of professional and amateur medical attention when in Spain, before death on the aeroplane and also at home before admission to hospital.…”

Section: Discussionmentioning

confidence: 99%

Pathology of five Scottish deaths from pneumonic illnesses acquired in Spain due to Legionnaires' disease agent.

Boyd¹,

Buchanan²,

Macleod³

et al. 1978

J Clin Pathol

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The pathology and histology are reported of five Scots who died of severe pneumonic illnesses after holidays in Spain, three in 1973 and two in 1977. There is strong evidence in favour of all the deaths having been due to the newly discovered Legionnaires' disease (LD) agent. The agent (or its soluble antigen) has been visualised in sections of lung tissue by fluorescent-antibody tests in all cases, and the agent has been identified by the Dieterle silver staining method in small numbers in all cases. Serological testing was possible in three of the patients, and two had very high antibody titres against the LD agent. Apart from the extensive and severe nature of the pathological process there is no feature to distinguish pulmonary infection by this agent from that due to more commonly known bacteria capable of causing lobar pneumonia. The severity and extensive nature of the process is partly a reflection of neglect in seeking treatment until late in the infection, and partly a reflection, as revealed in retrospect, on the use of the wrong antibiotic combination during treatment. Erythromycin has been recommended by other workers as the drug of choice against the LD agent. Infection by this organism is not confined to the USA or to Spain and is indigenous also in the United Kingdom.

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Section: Discussionmentioning

confidence: 99%

Pathology of five Scottish deaths from pneumonic illnesses acquired in Spain due to Legionnaires' disease agent.

Boyd¹,

Buchanan²,

Macleod³

et al. 1978

J Clin Pathol

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“…These authors refer to outbreaks in the Washington area and Pontiac (Michigan) while Macrae and Lewis (1977) refer to an outbreak in Nottingham, England, and Lawson et al (1977), Lawson (1978), and Reid, Grist and Natjera (1978) record the disease in Scottish tourists returning to Glasgow after holidays in Spain. The pathology of the deaths among these last cases has been reported (Boyd et al, 1978), and the pathology of the original Legionnaires' disease episode is also on record (Chandler et al, 1977;Blackmon et al, 1978).…”

Section: Discussionmentioning

confidence: 99%

A fatal case of Legionnaires' disease originating in Scotland

Lees

Tyrrell

Boyd

1979

Postgraduate Medical Journal

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Summary A 21-year-old female died in May 1976 from a pneumonic illness presenting with a right pleural effusion. Histopathology showed florid hyaline membrane disease of the left lung only, and focal pneumonitis in the lower lobe. Further investigations carried out by the Center for Disease Control, Atlanta, Georgia, showed that this patient had Legionnaires' disease infection, the first indigenous case diagnosed in Scotland. Post-mortem examination showed features differing from those in other published cases.

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“…The early efforts to unravel the epidemiology of Legionnaires' Disease focused on the investigation of localized outbreaks like the 1976 outbreak in Philadelphia. During 1977 and1978 additional outbreaks were recognized in several states (Table 1). Of interest, outbreaks occurring before July 1976 also were identified when frozen lung and serum specimens collected during previous epidemics of undiagnosed respiratory disease 001 l-9O59/83/O5OO/O239/$01.10 © Inlernalional Society of Tropical Dermatology, Inc were tested with the fluorescent antibody techniques.…”

Section: Pidemiologic Originsmentioning

confidence: 99%