Leiomiosarcoma pulmonar primario: presentación de un caso

Luthra, Munish; Khan, Hina; Suhail, Maham; Avadhani, Vaidehi

doi:10.1016/j.arbres.2012.01.006

Cited by 3 publications

(9 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…PPLs are difficult to diagnose. 6 They tend to expand locally in the lung parenchyma and thus mimic more common nonsarcomatous tumors in their clinical and macroscopic presentation in addition to their appearance on radiographic imaging. 6 They do, however, have a tendency to rapidly expand.…”

Section: Diagnosismentioning

confidence: 99%

“…6 They tend to expand locally in the lung parenchyma and thus mimic more common nonsarcomatous tumors in their clinical and macroscopic presentation in addition to their appearance on radiographic imaging. 6 They do, however, have a tendency to rapidly expand. 2 Plain films of the chest typically demonstrate a well-circumscribed, smooth, or lobulated round mass.…”

Section: Diagnosismentioning

confidence: 99%

“…1 In making the diagnosis of PPL, it is important to first rule out the possibility of a secondary source of the neoplasm, especially considering that extrapulmonary sarcoma metastases are more common than tumors of primary origin. 6 Histological examination of tissue samples remains the standard for diagnosing PPLs, 5 especially considering the difficulty of obtaining useful data from other modalities. Leiomyosarcomas typically travel through the bloodstream and occasionally the lymphatics, and they rarely exfoliate.…”

Section: Diagnosismentioning

confidence: 99%

“…This behavior makes it unlikely to obtain meaningful samples from bronchoscopy and washings/ brushings, and mediastinoscopy is not useful in making a definitive diagnosis because leiomyosarcomas typically metastasize via the blood or lymph. 6 Pleural fluid samples also provide little value in the diagnostic process. 6 The use of immunohistochemistry staining can also augment the process of diagnosis and classification of sarcomas.…”

Section: Diagnosismentioning

confidence: 99%

“…6 Pleural fluid samples also provide little value in the diagnostic process. 6 The use of immunohistochemistry staining can also augment the process of diagnosis and classification of sarcomas. For leiomyosarcomas in particular, staining is positive for vimentin, 5 desmin, 5 and actin 1 in approximately 60% of patients with this neoplasm.…”

Section: Diagnosismentioning

confidence: 99%

See 4 more Smart Citations

Bilateral Primary Pulmonary Leiomyosarcoma: A Case Report

Magovern

Wachs

Malatack

2019

Georgetown Medical Review

View full text Add to dashboard Cite

Introduction: Primary pulmonary leiomyosarcomas are a group of rare malignant tumors. They are subdivided into those originating from pulmonary parenchyma, bronchial tree, or pulmonary arteries. They tend to expand locally, and presentation depends on the site of the tumor. Diagnosis can be challenging. Case Presentation: A 40-year-old woman presented with dyspnea and severe sepsis due to a lung mass and postobstructive pneumonia. She was diagnosed as having bilateral endobronchial primary pulmonary leiomyosarcoma and treated with bilobectomy; however, she died shortly after surgery due to complications. Conclusion: Considering the rarity of her condition, this case offers a unique opportunity to investigate its presentation, diagnosis, and treatment strategies through a study of the literature.

show abstract

Section: Diagnosismentioning

confidence: 99%

Section: Diagnosismentioning

confidence: 99%

Section: Diagnosismentioning

confidence: 99%

Section: Diagnosismentioning

confidence: 99%

Section: Diagnosismentioning

confidence: 99%

See 3 more Smart Citations

Bilateral Primary Pulmonary Leiomyosarcoma: A Case Report

Magovern

Wachs

Malatack

2019

Georgetown Medical Review

View full text Add to dashboard Cite

show abstract

Primary pulmonary leiomyosarcoma with coexistent pulmonary aspergillosis: a case report

Badheeb¹,

Gharem²,

Hammadi³

et al. 2022

Pan Afr Med J

View full text Add to dashboard Cite

Coexisting primary pulmonary leiomyosarcoma (PPL) with pulmonary Aspergillosis in immunocompetent patients is a rare occurrence. Here, we presented a 54-year-old woman presented with a dry cough for two months. Bronchoscopy revealed pulmonary aspergillosis. The patient was treated with antifungal therapy for one month without improvement. To evaluate further, a chest computed tomography (CT) scan showed a large heterogeneous enhancing mass in the lower lobe of the left lung with left atrium thrombosis. Computed tomography-guided biopsy was performed, and histopathology demonstrated the diagnosis of PPL. The metastasis workup staging showed multiple metastases in vertebrae, scapula, rib, and liver. The patient was treated with chemotherapy followed by tumor bed radiotherapy. Unfortunately, her general condition worsened, and she passed away with overall survival of fourteen months. In conclusion, clinicians should be alert to underlying malignant disease if airway Aspergillus infection is suspicious in patients without strong risk factors for invasive fungal infection.

show abstract