Leiomyoma of kidney: An Indian experience with literature review

Mitra, Bhaskar; Debnath, Sharmistha; Pal, Mallika; Paul, Biswanath; Saha, Tarak Nath; Maiti, Ananda

doi:10.1016/j.ijscr.2012.07.015

Cited by 13 publications

(9 citation statements)

References 19 publications

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“…Although the vast majority of kidney leiomyoma cases reported in the literature are adults, they may also be detected in childhood. Leiomyomas are two times more common in women than men, and the incidence increases after the fourth decade of life (3,5). In our series, leiomyoma was detected equally in both men and women.…”

Section: Discussionsupporting

confidence: 41%

“…The patient was followed-up for 14 months and, serum creatinine and eGFR levels were 1.12 mg/dL and 44 mL/min/1.73 m 2 , respectively. genitourinary tract organs including smooth muscle cells, such as ureter, bladder, urethra, prostate, seminal vesicles, testicles, penis and scrotum (5). Renal leiomyomas are extremely rare benign tumors of the kidney with a prevalence of up to 5%, based on incidental findings of autopsy series.…”

Section: Casementioning

confidence: 99%

See 1 more Smart Citation

Challenges in Differential Diagnosis: A Case Series of Four Adult Patients with Renal Leiomyoma

Mercimek¹,

Özden²,

Yakupoğlu³

2019

uob

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terms of clinical, radiological evaluation, surgical management, and histopathological and immunohistological assessment. Case Reports This study was conducted in accordance with the declaration of Helsinki. All patients read the patient information form and written informed consents were obtained. Case 1: A 45-year-old woman with a history of open uterine myomectomy five years ago presented with pain in the left lower quadrant for one week. Physical examination, urine and blood analyses were normal. Abdominal ultrasonography (US) revealed a 5 cm mass in the lower pole of the right pelvic ptotic kidney. Further imaging with computerized tomography (CT) was performed and revealed a completely exophytic, wellcircumscribed, homogeneously contrast enhancing, 6x5 cm renal mass (Figure 1A and Figure 2). Since renal cell carcinoma could not be ruled out, laparoscopic partial nephrectomy was carried out for the management of the renal mass. Postoperative course was uneventful and the patient was discharged on the 3 rd post-operative day. Pathological gross examination of the surgical specimen revealed a 7x5x4 cm fibrillary mass in the form of a benign smooth muscle tumor with a hard-rubbery Leiomyomas are rare, benign and solid tumors of the kidney. Although the developments in radiological imaging methods provide early detection of kidney tumors, it is difficult to differentiate leiomyomas radiologically from other malignant renal tumors. Moreover, the definitive diagnosis of leiomyomas can only be achieved by histopathological and also immunohistochemical evaluation after surgical intervention. Immunohistochemically, positive staining with smooth muscle actin and vimentin, whereas negative staining with cytokeratin, S100, Mart1 and HMB45 are the methods used in the differential diagnosis of leiomyomas. In this case series, after preoperative radiological evaluation, two female and two male patients between 45 and 89 years of age underwent laparoscopic treatment with the diagnosis of a malignant mass in the kidney. We aimed to illustrate the clinical, radiological and histopathological relationship of four adult patients who were managed by laparoscopic approach and diagnosed with renal leiomyoma. Renal leiomyomas should be kept in mind in patients with a renal mass before definitive treatment.

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Section: Discussionsupporting

confidence: 41%

Section: Casementioning

confidence: 99%

Challenges in Differential Diagnosis: A Case Series of Four Adult Patients with Renal Leiomyoma

Mercimek¹,

Özden²,

Yakupoğlu³

2019

uob

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“…21 The quantitative analysis in this case showed that the mass was hypervascular in relation to the native kidney parenchyma and hypovascular in relation to the kidney graft. Given that guidelines from urologic associations always include CT evaluation of renal masses, we compare CEUS features with those of CT. Based on data reported in the literature, it is well known that enhancement of renal tumors has a different pattern according to renal function: RCCs are characteristically well vascularized in comparison with the renal parenchymal vascular sclerosis in chronic kidney disease, 22 and leiomyomas in patients with normal kidney function are less vascularized than the renal parenchyma, 23,24 quite the opposite pattern from that observed in this case using CEUS.…”

Section: Ceus Was Useful For Diagnosis and Evaluation Of The Renal Macontrasting

confidence: 50%

Imaging Features of Renal Capsule Leiomyoma on Contrast-Enhanced Ultrasonography: A Case Report

Moura-Neto

Souza

Suassuna³

et al. 2017

Journal of Diagnostic Medical Sonography

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Leiomyomas of the kidney are rare, mostly occurring in adults as incidental findings, and are a diagnostic challenge. In a renal transplant recipient population, an increased risk of tumors is observed due to the effect of immunosuppressive drugs. A differential diagnosis between leiomyomas and other malignant lesions is not possible with current imaging methods. This report presents a case of a native kidney capsular leiomyoma in a kidney transplant recipient and highlights the features of computed tomography and contrast-enhanced ultrasound (CEUS), along with the histopathologic analysis. The CEUS and quantification studies are helpful in demonstrating the vascularization pattern of the renal capsular leiomyoma. This entity appearing with chronic kidney disease can resemble a renal cell carcinoma, in an otherwise healthy kidney. In this case, CEUS was useful for diagnosing the vascularization of the renal mass, although the pattern of intense vascularization could be diagnostically misleading, implying a malignant lesion. However, the pattern of enhancement due to CEUS showed no peculiarities that indicated histopathologic diagnosis.

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“…Renal leiomyoma could occur in capsular, parenchyma, or pelvis locations [ 20 ]. On images, renal leiomyomas usually present as solid tumors, although they could have cystic degeneration as well [ 20 ]. Renal leiomyomas are more common in women [ 20 ].…”

Section: Key Diagnostic Featuresmentioning

confidence: 99%

“…On images, renal leiomyomas usually present as solid tumors, although they could have cystic degeneration as well [ 20 ]. Renal leiomyomas are more common in women [ 20 ]. On computed tomography, renal leiomyomas are usually well defi ned and homogeneously enhanced less than normal parenchyma.…”

Section: Key Diagnostic Featuresmentioning

confidence: 99%

Renal Parenchymal Neoplasms

Wang

2014

Key Diagnostic Features in Uroradiology

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Leiomyoma of kidney: An Indian experience with literature review

Abstract: Considering the difficulty of clinical diagnosis of this tumour, strong suspicion is indicated when a patient presents with voluminous, well circumscribed renal lesions.

Cited by 13 publications

References 19 publications

Challenges in Differential Diagnosis: A Case Series of Four Adult Patients with Renal Leiomyoma

Challenges in Differential Diagnosis: A Case Series of Four Adult Patients with Renal Leiomyoma

Imaging Features of Renal Capsule Leiomyoma on Contrast-Enhanced Ultrasonography: A Case Report

Renal Parenchymal Neoplasms

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