Leiomyoma of the Cheek

Abstract

Leiomyomas are rare benign tumors that grow in the tunica media of smooth muscle cells. Leiomyomas occur most frequently in the uterus or gastrointestinal tract and only very rarely in the area of the cheek. This study reports on a rare case of a leiomyoma in the cheek of a 43-year-old woman, who presented with a well-circumscribed, asymptomatic, mobile swelling in the right cheek. This swelling was slightly purplish in color and measured approximately 4 cm×3 cm. Surgical excision was the treatment of choice, and the diagnosis was based on histopathological and immunohistochemical stains, which were positive for actin and desmin and negative for AE1/AE3, CD34, and S100. The patient’s follow-up, two years later, showed no recurrence, and she has been asymptomatic since the surgery.

Oral Leiomyoma in a Pediatric Patient: A Diagnostic Challenge

“…A debatable pathogenesis of leiomyoma is available in the literature, although traumatic injury, venous stasis, hormonal alterations, and genetic changes can be considered. They usually occur in the fourth and fifth decades of life and on the lips, buccal mucosa, or tongue [ 9 ]. In our case, it was noticed in a 12-year-old boy on the right dorsal surface of the tongue.…”