Leiomyoma of the Testis

Abstract

Testis leiomyoma is a very rare neoplasm. It is very difficult to perform an exact preoperative diagnosis; only histological examination can prove the presence of a leiomyoma. In our case radical orchidectomy was performed because of complete substitution of normal parenchyma, the extreme rarity at long-term follow-up of a reported benign intratesticular neoplasm, and the imperfect sensitivity of the extemporary histological examination.

Myoid gonadal stromal tumor: a distinct testicular tumor with peritubular myoid cell differentiation

“…In this regard, most reported testicular leiomyomas arise in tunica albuginea and paratesticular regions such as scrotum or spermatic cord [3], which are usually extratesticular and exophytic with connection to testis. Nonetheless, intratesticular leiomyomas have been reported [3,[9][10][11][12][13]. Our literature review revealed 6 such cases that were reported as intratesticular leiomyomas (Table 3).…”

“…Unfortunately, most of these tumors were not thoroughly characterized using modern techniques, such as electron microscopy and immunohistochemistry. For example, 4 cases were classified as leiomyomas solely based on H&E histology [3,9,10,12], and in 2 others, SMA was reported as positive [11,13]. It is significant that the intratesticular leiomyoma reported by Honore and Sullivan [3] was postulated to be of PTMC origin.…”

Leiomyoma of Testis –A Case Report

“…It is very difficult to perform an exact preoperative diagnosis; only histological examination can prove the presence of a leiomyoma. A radical orchidectomy was performed because of complete substitution of normal parenchyma, the extreme rarity at long-term follow-up of a reported benign intratesticular neoplasm, and the imperfect sensitivity of the extemporary histological examination [6].…”

Leiomyoma of the testis: A rare testicular mass

“…Sonography has a reported accuracy of 95-100% in differentiating between tumors of intra-and extratesticular origin. 3 The rate of malignancy of intratesticular masses is between 90% and 95%, 4 whereas extratesticular lesions are usually benign masses or the result of inflammation or trauma. 5 Imaging of intratesticular lesions can rarely distinguish a benign from a malignant tumor, and most patients undergo orchiectomy prior to a diagnosis being established.…”