Leiomyosarcoma arising from the ovarian vein as a gynecologic malignancy: Two case reports and a review of the literature

Yokoyama, Yasuhiro; Goda, Tomohiro; Sato, Kazuki; Suzuki, Mariko; Kanda, Tomoyuki; Sato, Yasumasa

doi:10.1111/jog.15242

Cited by 2 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It can be challenging to differentiate IVL from primary leiomyosarcoma at an early stage due to similar clinical and radiological manifestations. Leiomyosarcoma is known to grow from the wall of the inferior vena cava, which tends to involve the vascular walls and adjacent tissues (48). IVL, by contrast, has a clear boundary with no adhesion to the vascular walls.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…IVL, by contrast, has a clear boundary with no adhesion to the vascular walls. Men account for a large proportion of the patients with leiomyosarcoma, especially primary vascular leiomyosarcoma in the extremities (34,48). Right atrial myxoma only occurs in the heart chamber with a stalk and may attach to the walls of the cardiac chambers and not affect the inferior vena cava, while IVL, typically originating from the uterus, has a serpentine appearance, with iliac or ovarian vein extension into the inferior vena cava and right atrium.…”

Section: Differential Diagnosismentioning

confidence: 99%

See 1 more Smart Citation

Update on clinical characteristics and molecular insights for uterine intravenous leiomyomatosis (Review)

Zhou,

Qi,

Zhao

et al. 2023

Oncol Lett

View full text Add to dashboard Cite

Intravenous leiomyomatosis (IVL) is a rare benign disease, which typically develops along vascular vessels and extends to the inferior vena cava and right atrium of the heart. In the early stages of the disease, the clinical manifestations and the results of imaging examinations are not uniform among patients. Thus, a high rate of misdiagnosis and missed diagnosis is common. When the tumor extends along the venous system to the pelvic floor vein or through the inferior vena cava involving the right atrium of the heart or the pulmonary artery, severe symptoms occur, such as ascites, dyspnea, heart failure and even sudden mortality. Improving the understanding of IVL to identify and evaluate this disease in its early stages is important. Complete tumor resection remains the primary treatment option for IVL. The recurrence rate of the disease varies depending on multiple factors, such as type of surgical procedure performed. Therefore, long-term follow-up is necessary for patients with IVL. The review of recent findings on the molecular and clinicopathological characterization of IVL is important to understand the pathogenesis of IVL. In the present study, the clinical manifestations, pathogenesis, differential diagnosis, treatment and prognosis of IVL are summarized in order to provide a single source of insightful information on IVL.

show abstract

Section: Differential Diagnosismentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

Update on clinical characteristics and molecular insights for uterine intravenous leiomyomatosis (Review)

Zhou,

Qi,

Zhao

et al. 2023

Oncol Lett

View full text Add to dashboard Cite

show abstract

“…Primary RVLMS of the ovarian vein is an unusual condition; only about 23 cases have been recorded [ 6 - 12 ]. Despite our extensive review of English literature, we could not find any similar case of RVLMS of the gonadal vein in a male patient.…”

Section: Discussionmentioning

confidence: 99%

Primary Leiomyosarcoma of the Ovarian Vein Causing Obstructive Uropathy: A Case Report

Hajji¹,

Azami²,

Adlouni³

et al. 2022

Cureus

View full text Add to dashboard Cite

Retroperitoneal vascular leiomyosarcoma (RVLMS) are rare soft-tissue sarcomas that most commonly arise from large blood vessels and have a poor prognosis. We present the case of a 61-year-old woman who presented with isolated left flank pain. Abdominal computed tomography and magnetic resonance imaging revealed a 5 cm retroperitoneal soft-tissue mass that was contiguous with the left ovarian vein and connected to the proximal ureter, causing hydronephrosis. As ureteroscopy suggested extrinsic compression of the ureter, a percutaneous biopsy of the mass was obtained, whereupon diagnosis of leiomyosarcoma was made. Radical en-bloc excision of the tumor, including the involved upper urinary tract and the gonadal vein, was performed. The tumor proved to be a leiomyosarcoma arising from the ovarian vein wall. No adjuvant therapy was planned, and no recurrence was noticed at her 24-month follow-up. Primary RVLMS of the ovarian vein is an uncommon condition. To date, only a few sporadic cases have been reported in the literature. What makes the present case further interesting is the unusual tumor’s relationship with the patient’s ureter, raising both diagnostic and management challenges. To our best knowledge, this is so far the fourth reported case of its kind to cause ureteral obstruction.

show abstract

Leiomyosarcoma arising from the ovarian vein as a gynecologic malignancy: Two case reports and a review of the literature

Cited by 2 publications

References 20 publications

Update on clinical characteristics and molecular insights for uterine intravenous leiomyomatosis (Review)

Update on clinical characteristics and molecular insights for uterine intravenous leiomyomatosis (Review)

Primary Leiomyosarcoma of the Ovarian Vein Causing Obstructive Uropathy: A Case Report

Contact Info

Product

Resources

About