Leiomyosarcoma of cervical stump following subtotal hysterectomy

Sturdy, D. E.

doi:10.1002/bjs.18004619812

Cited by 10 publications

(1 citation statement)

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“…In the author's opinion, deference should be given to a corpus location in cases that are truly equivocal. However, reported examples of cervical leiomyosarcomas that developed in the cervical stump after supracervical hysterectomies provide sufficient evidence that leiomyosarcomas may indeed arise from this site [ 6 , 7 ] Approximately 30 cervical leiomyosarcomas have been reported [ 3 , 6 - 27 ]. They generally occur in the perimenopausal and postmenopausal population in their 4 th to 6 th decades of life.…”

Section: Introductionmentioning

confidence: 99%

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Fadare

2006

Diagn Pathol

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Sarcomas constitute less than 1% of all cervical malignancies. With over 150 reported cases, rhabdomyosarcomas represent the most commonly reported sarcoma at this location. In this report, a select group of the more uncommon sarcomas of the uterine cervix are reviewed, including all previously reported examples of leiomyosarcoma, liposarcoma, alveolar soft part sarcoma, Ewing sarcoma/primitive neuroectodermal tumor, undifferentiated endocervical sarcoma, and malignant peripheral nerve sheath tumor (MPNST). Emphasis is placed on any distinctive clinicopathologic features of these entities at this unusual location.

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Section: Introductionmentioning

confidence: 99%

Untitled

Fadare

2006

Diagn Pathol

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Sarcomas and carcinosarcomas of the uterine cervix

Abell¹,

G²

1973

Cancer

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The clinical findings, pathologic characteristics, and end results of 26 primary sarcomas and carcinosarcomas of uterine cervix, excluding malignant lymphomas, embryonal rhabdomyosarcomas of infancy and childhood, and four sarcomas that could not be definitely classified as to cell type, are presented. Eight neoplasms occurring in patients 31 to 61 years of age were leiomyosarcomas. Six of these patients died with massive pelvic recurrences and/or distant metastases irrespective of type of treatment within 2 years. Two patients are alive and free of disease 6 and 10 years after surgical excisions. Six patients whose age averaged 61 years had carcinosarcomas, and all succumbed to recurrent and metastatic disease within 15 months of diagnosis. In three patients, the sarcomatous component was homologous and in the other three heterologous. One neoplasm had, in addition to adenocarcinoma and squamous carcinoma, areas of adenocystic carcinoma. Twelve endocervical stromal sarcomas in patients averaging 54 years of age comprised the largest group in the series. The better differentiated neoplasms tended to remain localized and to have a better prognosis than the more poorly differentiated lesions which pursued aggressive courses. Four patients are alive and free of disease 2, 3, 11, and 18 years after surgical excisions and a fifth died of other causes after 16 years. Six patients died of recurrent and metastatic disease 2 to 24 months after diagnosis. At the present time, surgical removal of uterus and, when indicated, contiguous tissues and viscera offers the best hope of cure for cervical sarcomas and carcinosarcomas.

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Undifferentiated Sarcoma of the Uterine Cervix

Talerman

Pathak

1971

Intl J Gynecology & Obste

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Leiomyosarcoma of cervical stump following subtotal hysterectomy

Cited by 10 publications

References 0 publications

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Sarcomas and carcinosarcomas of the uterine cervix

Undifferentiated Sarcoma of the Uterine Cervix

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