Leitlinie der DGAI zur allergischen Rhinokonjunktivitis

Bachert, Claus; Borchard, U.; Wedi, Bettina; Klimek, Ludger; Rasp, Gerd; Riechelmann, Herbert; Schultze‐Werninghaus, G.; Wahn, Ulrich; Ring, Johannes

doi:10.5414/alp26147

Cited by 17 publications

(32 citation statements)

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“…Andere Ursachen nasaler Symptome müssen ausgeschlossen werden. Diesbezüg-lich wird auf entsprechende Positionspapiere der Fachgesellschaften verwiesen [2,10,23,29]. Bei schmalem Sensibilisierungsmuster ist der Erfolg der SIT weitaus größer.…”

Section: Allergische Rhinitisunclassified

“…Gerade bei der perennialen Symptomatik ist daher der Ausschluss einer vasomotorischen Instabilität, von Infekten sowie einer nichtimmunologischen Hypersensitivität (z. B. auf Aspirin) besonders bedeutsam [2,13].…”

Section: Allergische Rhinitisunclassified

“…Symptomscores und Verbrauch von Asthmamedikamenten im Vergleich zu Placebo [1]. Dagegen zeigte sich keine Verbesserung der Lungenfunktion,obwohl die inhalative Reaktion auf spezifische Allergene reduziert war [2,13].…”

Section: Asthmaunclassified

“…Doch trotz des guten Sicherheitsprofils sowie einiger Befürworter und den Angaben der Hersteller besteht derzeit in der Fachwelt die Ansicht, dass die Datenlage noch zu spärlich ist, um die sublinguale SIT als zuverlässige Alternative der subkutanen SIT anzusehen [2,3,8,13,17,30].Insbesondere fehlen Daten zur optimalen Dosis und Behandlungsdauer,zur präventiven Wirkung,zum Langzeiteffekt,zur Patientencompliance sowie Vergleichsstudien zur subkutanen SIT ("double-blind double-dummy"). In den USA sind bisher keine sublingualen Allergenvakzinen im Handel [18], wohingegen der Einsatz der SLIT in Europa (v. a. in Südeuropa) deutlich zunimmt [8].…”

Section: Lokale Situnclassified

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Spezifische Immuntherapie

Wedi

Kapp

2004

Der Hautarzt

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Successful allergen-specific immunotherapy (SIT) induces complex immunologic chan-ges resulting in reduced allergic inflammatory reactions. SIT has long-term effects in mild forms of inhalant allergies and is effective even when standard pharmacotherapy fails. Moreover, the risk to develop additional allergic sensitizations and the development of asthma is significantly reduced in children with allergic rhinitis. SIT is the treatment of choice in patients with systemic reactions to hymenoptera venoms. Although the exact effector mechanisms of SIT still have to be clarified, the most probable effect is a modulation of regulatory T cells associated with a switch of allergen-specific B-cells towards IgG4 production. The critical point to insure efficacy and safety is the selection of patients and allergens, task best performed by a specialist trained in allergology. Further details are available in the position papers of the German allergy societies - DGAI(Deutsche Gesellschaft fiir Allergologie und Klinische Immunologie) and ADA (Arzte-verband Deutscher Allergologen) - which can be found at www.dgaki.de.

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Section: Allergische Rhinitisunclassified

Section: Asthmaunclassified

Section: Lokale Situnclassified

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Spezifische Immuntherapie

Wedi

Kapp

2004

Der Hautarzt

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“…Additional aspects concern financial burdens of patients and society or social constraints, such as activity limitations and a higher frequency of visits to physicians [5]. Furthermore, SAR increases the risk of developing further diseases, such as upper respiratory tract infections, mainly atopic dermatitis and asthma [5,11,12]. It might be that the rising prevalence of asthma is not caused by pollen allergens directly but by pollen-induced rhinitis [11].…”

Section: Introductionmentioning

confidence: 99%

Homeopathic Complex Remedy in the Treatment of Allergic Rhinitis: Results of a Prospective, Multicenter Observational Study

Trompetter

Lebert²,

Weiss³

2015

Complement Med Res

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Background: Seasonal allergic rhinitis (SAR), also known as hay fever, is a widespread chronic respiratory disease. In treatment of SAR the use of complementary therapies is increasing, but little has been published about homeopathic complex remedies so far. Therefore, we think it is time to conduct and publish an appropriate observational study. Methods: Course of single symptoms, impairment of quality of life, general efficacy, and tolerability of a homeopathic complex remedy containing active substances on a low dilution level have been assessed and analyzed. Altogether, 123 patients with a history of allergic rhinitis of up to 45 years have been observed for about 4 weeks. Results: The majority of symptoms were shown to improve substantially and the patients' quality of life increased clearly. The overall symptom score decreased significantly from 10.3 ± 4.7 to 3.9 ± 3.1 points (p < 0.0001), and reduction of impairment of quality of life from 5.7 ± 2.3 to 1.9 ± 1.8 score points was also significant (p < 0.0001). Rating of efficacy of study medication was markedly better than efficacy rating of previous therapies (p = 0.0193). Apart from one temporary allergic reaction, the treatment was well tolerated. Conclusion: The homeopathic complex remedy (Pascallerg®) tested in this observational study offers a useful option in treatment of SAR in children and adults.

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Die Anwendung lipidhaltiger Nasensalbe bei allergischer Rhinitis — eine Therapieoption?

Geisthoff

Rupp-Classen²,

Blum

et al. 2005

HNO

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The test agent used in our study contains a lipid fraction, in this case in the form of high purity, long chain hydrocarbons. By local application, a significant improvement of the total symptomatology was shown. The mechanism has not been clarified. Owing to the efficacy and low risk of side effects, this seems to be a promising adjuvant therapy for allergic rhinitis. The probetoric use of this nasal ointment as a supportive therapeutic option should be reviewed in further clinical studies.

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Leitlinie der DGAI zur allergischen Rhinokonjunktivitis

Cited by 17 publications

References 0 publications

Spezifische Immuntherapie

Spezifische Immuntherapie

Homeopathic Complex Remedy in the Treatment of Allergic Rhinitis: Results of a Prospective, Multicenter Observational Study

Die Anwendung lipidhaltiger Nasensalbe bei allergischer Rhinitis — eine Therapieoption?

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