Lemierre syndrome: Study of 11 cases and literature review

“…Lemierre's disease was first reported in 1890,4 5 and the syndrome was characterised by Andre Lemierre in 1936 as recent oropharyngeal infection with consequent thrombophlebitis of surrounding veins resulting in metastatic septic emboli 4–7. It is a rare phenomenon, estimated at around 1–3 cases per million per year and primarily affects children and young adults 8 9…”

Section: Discussionmentioning

confidence: 99%

Coexisting pulmonary haemorrhage and venous thrombosis: a tricky but novel case

Fielding¹,

Pecheva

Farghal

et al. 2016

BMJ Case Reports

View full text Add to dashboard Cite

We present a case of Lemierre's disease complicated by pulmonary artery pseudoaneurysm. A previously well woman aged 43 years presented with a history of a sore throat and worsening dyspnoea. She was diagnosed with a severe cavitating bilateral pneumonia complicated by internal jugular vein thrombosis consistent with a diagnosis of Lemierre's disease. She had an episode of massive haemoptysis which was confirmed to be due to a pulmonary artery pseudoaneurysm which required radiologically guided embolisation. She then required surgical decortication for bilateral empyemata. Blood cultures revealed growth of Slackia exigua, an organism yet to be linked with both of these complications concurrently. We believe this to be a novel case of this bacterium causing thrombosis and haemorrhage.

show abstract

“…1,2) This disease is often caused by an acute oropharyngeal infection with a secondary thrombophlebitis of the internal jugular vein, 3,4) and is sometimes followed by a dental extraction, 5) mastoiditis, 6) and otitis media. 6) The postanginal septic infection was first reported by Courmont and Cade in 1890.…”

Section: Introductionmentioning

confidence: 99%

Lemierre Syndrome Associated with Ipsilateral Recurrent Laryngeal Nerve Palsy: A Case Report and Review

Miyamoto

Toi

Kotani

et al. 2016

NMC Case Report Journal

View full text Add to dashboard Cite

Lemierre syndrome (LS) is a rare life-threatening disease that is often caused by an acute oropharyngeal infection with a secondary thrombophlebitis of the internal jugular vein. LS rarely manifests as cranial nerve palsy. To the best of our knowledge, this is the second case report of LS associated with recurrent laryngeal nerve palsy. A 66-year-old female presented to a dental clinic with gingivitis and sore throat. Due to moderate periodontitis, her left first upper molar was extracted. A few days later, she subsequently developed a coarse voice and occipital headaches, and was referred to an otolaryngologist. She was diagnosed with left recurrent laryngeal nerve palsy and subsequent left-sided otitis media, and was referred to us for persistent headaches. She intermittently presented with high-grade fever and complained of salty taste disturbance. Her head magnetic resonance imaging (MRI) revealed left mastoiditis, thrombosis in the left transverse and sigmoid sinus, and left internal jugular vein. Her laboratory tests revealed an elevated white blood cell count, levels of C-reactive protein, and D-dimer. No endogenous coagulopathy was confirmed. Although, blood and cerebrospinal fluid culture grew no microorganisms, respectively, the empirically determined antibiotic therapy was initiated. In a week, the patient defervesced and had no headaches despite persistent thrombosis. Early diagnosis and an immediate antibiotic treatment are crucial for LS patients. Anticoagulation therapy was not needed for our patient and is still controversial for LS.

show abstract

Lemierre syndrome: Study of 11 cases and literature review

Abstract: Treatment with broad-spectrum antibiotics is the primary choice of treatment of Lemierre syndrome. Surgery is indicated in case of abscess formation.

Cited by 58 publications

References 33 publications

Infections caused by Fusobacterium in children: a 14-year single-center experience

Infections caused by Fusobacterium in children: a 14-year single-center experience

Coexisting pulmonary haemorrhage and venous thrombosis: a tricky but novel case

Lemierre Syndrome Associated with Ipsilateral Recurrent Laryngeal Nerve Palsy: A Case Report and Review

Contact Info

Product

Resources

About