Lens integrated with self-aligned variable aperture using pneumatic actuation method

Huang, Yu; Zhou, Guangyong; Sinha, Sujeet K.; Chau, Fook Siong; Shouhua, Wang

doi:10.1016/j.sna.2010.03.001

Cited by 6 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Polydimethylsiloxane (PDMS) is an elastomeric polymer with interesting properties for biomedical applications, including physiological indifference, excellent resistance to biodegradation, biocompatibility, chemical stability, gas permeability, good mechanical properties, excellent optical transparency and simple fabrication by replica moulding [ 1 , 2 , 3 , 4 , 5 ]. Due to these characteristics, PDMS has been widely used in micropumps [ 6 ], catheter surfaces [ 7 ], dressings and bandages [ 8 ], microvalves [ 9 ], optical systems [ 10 , 11 ], in the in vitro study of diseases [ 12 , 13 ], in implants [ 14 , 15 ], in microfluidics and photonics [ 16 , 17 , 18 , 19 ]. Moreover, soft-lithography technology has driven the use of PDMS in microelectromechanical systems (MEMS) applications and in microfluidic components [ 17 , 18 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Properties and Applications of PDMS for Biomedical Engineering: A Review

Miranda

Souza

Sousa

et al. 2021

JFB

366

170

View full text Add to dashboard Cite

Polydimethylsiloxane (PDMS) is an elastomer with excellent optical, electrical and mechanical properties, which makes it well-suited for several engineering applications. Due to its biocompatibility, PDMS is widely used for biomedical purposes. This widespread use has also led to the massification of the soft-lithography technique, introduced for facilitating the rapid prototyping of micro and nanostructures using elastomeric materials, most notably PDMS. This technique has allowed advances in microfluidic, electronic and biomedical fields. In this review, an overview of the properties of PDMS and some of its commonly used treatments, aiming at the suitability to those fields’ needs, are presented. Applications such as microchips in the biomedical field, replication of cardiovascular flow and medical implants are also reviewed.

show abstract

Section: Introductionmentioning

confidence: 99%

Properties and Applications of PDMS for Biomedical Engineering: A Review

Miranda

Souza

Sousa

et al. 2021

JFB

366

170

View full text Add to dashboard Cite

show abstract

“…These properties include biocompatibility, thermal and chemical stability, chemically inert, gas permeability, good mechanical properties, simplicity to handle and manipulate, and thermal and electrical insulator. For all of the above, it’s a material that has been widely used in the development of micropumps, microvalves, catheter surfaces, dressings and bandages, optical systems, implants, microfluidic devices, devices for drug delivery, DNA sequencing, and clinical diagnostic, etcetera [ 7 , 8 , 9 , 10 , 11 , 12 ]. However, PDMS in biological environments can result in bacterial fouling or incompatibility due to its hydrophobic characteristics that help the adhesion of microorganisms [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Binary Graft of Poly(acrylic acid) and Poly(vinyl pyrrolidone) onto PDMS Films for Load and Release of Ciprofloxacin

2023

View full text Add to dashboard Cite

Polymers are versatile compounds which physical and chemical properties can be taken advantage of in wide applications. Particularly, in the biomedical field, polydimethylsiloxane (PDMS) is one of the most used for its high biocompatibility, easy manipulation, thermal, and chemical stability. Nonetheless, its hydrophobic nature makes it susceptible to bacterial pollution, which represents a disadvantage in this field. A potential solution to this is through the graft of stimuli-sensitive polymers that, besides providing hydrophilicity, allow the creation of a drug delivery system. In this research, PDMS was grafted with acrylic acid (AAc) and vinyl pyrrolidone (VP) in two steps using gamma radiation. The resulting material was analyzed by several characterization techniques such as infrared spectroscopy (FTIR), swelling, contact angle, critical pH, and thermogravimetric analysis (TGA), demonstrating the presence of both polymers onto PDMS films and showing hydrophilic and pH-response properties. Among the performed methods to graft, the loading and release of ciprofloxacin were successful in those samples obtained by direct irradiation method. Furthermore, the antimicrobial assays showed zones of inhibition for microorganisms such as Staphylococcus aureus and Escherichia coli.

show abstract