Lens-Sparing Vitrectomy for Progressive Tractional Retinal DetachmentsAssociated With Stage 4A Retinopathy of Prematurity

Vitreoretinal surgery for advanced retinopathy of prematurity: Presentation and outcomes from a developing country

“…Because our ROP program was relatively young, we were conservative in offering vitreous surgery to only the stage 4b and 5 patients. 21,22 In the published literature, there are not many series assessing the outcome of pars plana vitrectomy in advanced ROP cases. Few studies focused on assessing the rates of retinal reattachment only in stage 4a cases.…”

“…Few studies focused on assessing the rates of retinal reattachment only in stage 4a cases. [21][22][23] Some had enormous sample sizes that included all cases with the surgery performed by multiple surgeons and by various techniques. 11,12 Meticulous assessment of vision by standard protocols was present in but a few.…”

“…11,12 Meticulous assessment of vision by standard protocols was present in but a few. 3,9,14,15,22 We studied the data of these studies to evolve our study design to assess the outcome in babies with stage 4 and 5 ROP with minimum effect of confounders and bias.…”

Neue therapeutische Ansätze in der Behandlung der Frühgeborenenretinopathie

“…Die funktionellen Ergebnisse waren mit einem Visus von ca. 0,3 sehr gut [5,33,42]. Im Stadium 4b und 5 konnte, in einer älteren Studie, durch eine Cerclage eine Netzhautanlage in 59 -75% erreicht werden [19].…”

“…Durch eine frühzeitige "lens sparing vitrectomy" im Stadium 4a können bessere anatomische und funktionelle Ergebnisse erreicht werden im Gegensatz zu einer Vitrektomie bei einem Stadium 5 [5,33,42]. Das Hauptproblem einer Vitrektomie im Stadium 4 ist jedoch die noch hohe vaskuläre Aktivität, welche den OP-Verlauf ungünstig beeinflussen kann.…”