Lentigo Maligna in a Woman With Oculocutaneous Albinism

Stoll, D

doi:10.1001/archderm.1981.01650060050023

Cited by 23 publications

(2 citation statements)

References 9 publications

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“…Although uncommon in albinos, melanoma has been reported in both tyrosinase‐positive and tyrosinase‐negative forms of OCA 55–58 . It is interesting to note that one albino patient was found to have melanoma and dysplastic nevus syndrome 56 …”

Section: Complicationsmentioning

confidence: 99%

Oculocutaneous albinism

Okulicz

Shah

Schwartz

et al. 2003

Acad Dermatol Venereol

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Oculocutaneous albinism represents a group of inherited skin disorders characterized by a generalized reduction of cutaneous, ocular and pilar pigmentation from the time of birth. Oculocutaneous albinism types 1 and 2 are the most common, but several other types have been described. A defect in the melanin synthesis pathway, resulting in reduced formation of melanin, is responsible for oculocutaneous albinism. Aetiology, clinical manifestations, diagnosis and management are discussed.

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Section: Complicationsmentioning

confidence: 99%

Oculocutaneous albinism

Okulicz

Shah

Schwartz

et al. 2003

Acad Dermatol Venereol

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“…LM has been reported in association with several conditions, including porphyria cutanea tarda (38), Werner syndrome (39), tyrosinase‐positive oculocutaneous albinism (40), and xeroderma pigmentosum (41,42). Cigarette smoking does not appear to be associated with the development of LM (43).…”

Section: Epidemiologymentioning

confidence: 99%

Lentigo maligna

Smalberger¹,

Siegel

Khachemoune

2008

Dermatologic Therapy

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Lentigo maligna (LM), a melanoma in situ, is a fairly common melanocytic lesion that usually develops on the chronically sun-exposed skin of the head and neck of Caucasians. It occurs mostly in people older than 40 years, with an incidence rate that increases with age and peaks in the seventh and eighth decades of life. Its diagnosis and treatment remain challenging. In this article, we review the history, epidemiology, clinical presentation, histology, and treatment of LM.

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Malignant Melanoma in Oculocutaneous Albinism

Schulze¹,

Rapini²,

Duvic

1989

Arch Dermatol

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1. Gupta AK, Matteson EL, Ellis CN, et al. Cyclosporine in the treatment of psoriatic arthritis. Arch Dermatol. 1989;125:507-510. 2. Ellis CN, Gorsulowsky DC, Hamilton TA, et al. Cyclosporine improves psoriasis in a double-blind study. JAMA. 1986;256:3110-3116. 3. Stern RS. Risk assessment of PUVA and cyclosporine. Arch Dermatol. 1989;125:545-547. Alternatives to PhotographyTo the Editor.\p=m-\The recent spate of articles on photography of dysplastic nevi certainly creates medicolegal problems. The standard of care must vary with the availability of elaborate equipment, facilities, and the cost. Although some patients have numerous suspicious lesions, most do not. It is about this latter group that I write. The Polaroid camera shots provide an accurate, immediate photograph of a suspicious lesion at a cost of about $2 (1989). Even such shots of ten lesions at $20 is far below the cost of $100 mentioned by Slue and Knopf1,2 (now $125). Also, consider that follow\x=req-\ up may be needed at 6to 12-month periods. I am further intrigued by identification of the location of the photographic lesion. There are alternative ways to do this without photography! A recent article mentioned the use of tattooing to permanently mark the location of an important lesion, especially those needing surgical attention, which has to be postponed for a variety of reasons, such as travel, intervening ill¬ nesses, finances, or search for a special or different physi¬ cian. I have found this type of tattooing to be very useful for many years. I have used india ink, although other markers can be considered, such as silver nitrate, graphite (lead pencil), or ferric chloride. A hypodermic needle, hammered flat, will pick up an adequate amount of india ink to make a permanent tiny mark. This flattened needle avoids exces¬ sive capillary filling. This mark is readily identified when looked for, yet is almost invisible to the casual eye. The tat¬ toos of black-skinned patients may be best done with silver nitrate solution.I learned my tattooing technique from Charlie Wagner and Harry the Horse-famous New York Bowery tattoo artists. Charlie told me he inserts his needle at an angle in order to "shovel" the material more effectively into the skin.My tutelage came about when it was popular to tattoo cinnabar (red) pigment into pruritic areas, especially for pruritis ani! My purpose in describing the use of tattoos in the care of dysplastic nevi is threefold, and will hopefully appeal as an easy, accurate, and low-cost method. I have long identified my patients' lesions by mentioning the area, such as malar, temple, right or left cheek, or ala nasi, followed by the measured (in centimeters) distance from two or even three prominent markers, such as the tragus, the inner canthus of the eye, or the cubital fossa.This localization is not only easy, but can be further helped by a tattooed number, if the lesion warrants. This number can be accurately accomplished by the use of the braille capital lettering system, such as we see in elevators. ...

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Lentigo Maligna in a Woman With Oculocutaneous Albinism

Cited by 23 publications

References 9 publications

Oculocutaneous albinism

Oculocutaneous albinism

Lentigo maligna

Malignant Melanoma in Oculocutaneous Albinism

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