2009
DOI: 10.1111/j.1524-4725.2009.01099.x
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Lentigo Maligna—Outcomes of Treatment with Q-Switched Nd:YAG and Alexandrite Lasers

Abstract: Although QS:Nd:YAG and alexandrite laser treatment of LM produced long-term clearance in 12 of the 22 patients, the ease and speed of this treatment and excellent cosmetic outcome achieved make this a suitable alternative to surgical excision, especially in elderly people, in treatment of large lesions, or in patients who refuse surgical treatment.

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Cited by 34 publications
(24 citation statements)
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“…Destructive techniques including cryotherapy, photodynamic therapy, ablative laser including carbon dioxide and Er:YAG lasers, electrodessication and curettage, and pigmenttargeting lasers such as Q-switched Nd:YAG and Alexandrite laser have been used, but with variable efficacy and insufficient evidence to draw meaningful conclusions [64][65][66][67][68]. Recurrence rates have ranged from 0-40% with cryosurgery, from 0-37.8% with various lasers, and 25-100% with electrodessication and curettage [40].…”
Section: • • Medical Managementmentioning
confidence: 99%
“…Destructive techniques including cryotherapy, photodynamic therapy, ablative laser including carbon dioxide and Er:YAG lasers, electrodessication and curettage, and pigmenttargeting lasers such as Q-switched Nd:YAG and Alexandrite laser have been used, but with variable efficacy and insufficient evidence to draw meaningful conclusions [64][65][66][67][68]. Recurrence rates have ranged from 0-40% with cryosurgery, from 0-37.8% with various lasers, and 25-100% with electrodessication and curettage [40].…”
Section: • • Medical Managementmentioning
confidence: 99%
“…After the discovery of the theory of selective photothermolysis, reports of QS lasers as treatment for LM began to surface. Since then, several case reports have documented both failures and successes with this therapy 22–26. Most recently, Madan et al published a series of 22 patients treated with QS Nd:YAG and Alexandrite lasers for LM 22.…”
Section: Discussionmentioning
confidence: 99%
“…Recurrence rates were 23% after a follow-up of \3 months. 103 When evaluated as a class of treatment, recurrence rates of MIS treated with laser were as high as 38%, with some progressing to LM melanoma. [103][104][105][106][107][108][109][110][111] A major challenge with laser therapy is the absence of histopathology to evaluate the presence of invasive components and confirmation of complete extirpation of the tumor.…”
Section: Staged Excision Key Pointsmentioning
confidence: 99%