“…Because of their exceptional mass transfer and large specific surface area, Pt-based nanodendrites have recently attracted considerable research interest. − Various Pt-based nanodendrites, such as Pt, Pd@Pt, PdPt 3 , Au@Pt, and Ag@Pt, exhibiting peroxidase-like activities have been identified. However, because of their limited catalytic activity toward H 2 O 2 , the peroxidase-like activity of Pt-based nanodendrites is inferior to that of HRP. − Recently, in Pt-based nanozymes, although the modulation of the Pt electronic structure through alloying with other transition metals, such as Au, Ru, Pd, Cu, and Ag, has produced diverse catalytic activities, , the morphology and size change because of variations in elemental composition during synthesis, and the relationship between the composition and peroxidase-like activity remains elusive, which poses challenges for designing highly active Pt-based nanodendrite nanozymes.…”