Leontiasis ossea

Chadwick, Nicholson S.; Baykal, Ahmet

doi:10.37549/ar2434

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…La afectación más frecuente se da en costillas, fémur, pubis, tibia, vértebras y clavículas. La forma facial es menos frecuente y se presenta como expansión progresiva, que puede ser dolorosa o no, asociada a ensanchamiento de los espacios interdentales, aplanamiento tanto de las fosas nasales como del puente nasal, y agrandamiento de la mandíbula 3 . Además, los pacientes sufren deterioro funcional, incluido el compromiso de los nervios craneales y la posible obstrucción de las vías respiratorias.…”

Section: Estimados Editoresunclassified

Hallazgos tomográficos en la uremia por hiperparatiroidismo secundario (leontiasis ósea)

Bello,

Perroni,

Bustamante

et al. 2023

RAR

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Section: Estimados Editoresunclassified

Hallazgos tomográficos en la uremia por hiperparatiroidismo secundario (leontiasis ósea)

Bello,

Perroni,

Bustamante

et al. 2023

RAR

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Uremic Leontiasis Ossea

Heard

Raj

et al. 2021

JCIS

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While renal osteodystrophy is a common complication of chronic renal failure which is caused by secondary hyperparathyroidism, it is rare that the bony changes result in a severe progressive overgrowth of the bones of the face such that the patient is at risk for breathing and feeding difficulties. When this occurs, it is called uremic leontiasis ossea and patients who suffer from this rare, severe complication of renal osteodystrophy may go undiagnosed or be misdiagnosed resulting improper management due to its limited discussion in the literature. We report a case of a 42-year-old man with end-stage renal disease who was unable to receive dialysis consistently for many years who was found to have a large hard mass on the palate and palate ulcers.

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Uremic Leontiasis Ossea: Theoretical Concepts and Practical Considerations

Sabanis,

Paschou,

Drylli

et al. 2022

Saudi Journal of Kidney Diseases and Transplantation

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Leontiasis ossea (LO) in chronic kidney disease patients, also known as Sagliker syndrome, is an exceptionally uncommon uremic complication of long-lasting and severe secondary hyperparathyroidism. The prominent features of uremic LO (ULO) encompass the characteristic clinical trial of massive thickening of maxillary and mandibular bones, widening of interdental spaces, and flattening of nasal bridges and nares. Moreover, during the transformation of craniofacial architecture, significant structural and functional consequences may appear, including upper airway patency, visual and hearing acuity, oral phase of swallowing as well as various neurological and psychiatric disorders. Only few cases of ULO have been reported in the literature until now, making challenging not only the traditional diagnostic procedures but also the optimal therapeutic approach. In this narrative review, we aim to explore the underlying pathophysiological mechanisms, summarize the evidence for adverse outcomes, and highlight the current therapeutic strategies for ULO prevention and treatment, given that precise genetic determinants remain elusive.

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Leontiasis ossea

Cited by 3 publications

References 9 publications

Hallazgos tomográficos en la uremia por hiperparatiroidismo secundario (leontiasis ósea)

Hallazgos tomográficos en la uremia por hiperparatiroidismo secundario (leontiasis ósea)

Uremic Leontiasis Ossea

Uremic Leontiasis Ossea: Theoretical Concepts and Practical Considerations

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