2000
DOI: 10.1046/j.1468-3083.2000.00076.x
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Lepromatous leprosy in an HIV‐positive patient in Spain

Abstract: We report a 35-year-old HIV-positive male affected by lepromatous leprosy which, to our knowledge, is the first case of its kind in Spain. The relationship between the two conditions is discussed.

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Cited by 9 publications
(4 citation statements)
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“…In Group 1, only 2 patients (5%) experienced this kind of reaction, but these 2 patients exhibited the borderline lepromatous clinical form. The cases that have been previously reported, in which a co-infected patient presents a Type 2 reaction, occurred in patients who were already severely immunosuppressed for a prolonged period of time, contrary to the situation of the patients observed in the present study [ 48 , 49 ].…”
Section: Discussioncontrasting
confidence: 99%
See 1 more Smart Citation
“…In Group 1, only 2 patients (5%) experienced this kind of reaction, but these 2 patients exhibited the borderline lepromatous clinical form. The cases that have been previously reported, in which a co-infected patient presents a Type 2 reaction, occurred in patients who were already severely immunosuppressed for a prolonged period of time, contrary to the situation of the patients observed in the present study [ 48 , 49 ].…”
Section: Discussioncontrasting
confidence: 99%
“…The treatment of these reactional states, including acute neuritis in the co-infected group, was performed using the same prescribed medication to patients with leprosy only, following the normative of the latest ministerial decree of 2010. This decree highlighted a preference for prednisone, at a dose of 1 mg/kg for Type 1 reactions, acute neuritis, and some cases of Type 2 reactions, and recommended the use of thalidomide for Type 2 reactions, with the exception of treating women of childbearing age [ 47 , 49 ]. Several published clinical studies also refer to the classical treatment of reactional states in co-infected patients, including an emphasis on the introduction of an appropriate dose of prednisone early to avoid scarring, especially in cases of acute neuritis and concomitant immune reconstitution inflammatory syndrome [ 17 , 18 , 31 , 41 , 50 ].…”
Section: Discussionmentioning
confidence: 99%
“…Sabese que incidência de hanseníase não é aumentada em pacientes infectados pelo HIV. [1][2][3][4][5][6][7][8] Nos casos descritos de associação entre hanseníase e Aids, não se pode afirmar que a infecção pelo HIV altere a evolução da hanseníase; pelo contrário, a maioria dos relatos FIGURA 1: Placa anular, eritêmato-pardacenta, de bordo elevado e centro deprimido, de 2cm de diâmetro, com pápulas e nódulos na periferia FIGURA 2: Detalhe da figura anterior demonstra não haver modificações clínica, imunológica ou histológica, e, portanto, não haveria necessidade de modificações nos programas de controle da hanseníase. 4 Há autores que relatam maior número de reações tipo eritema nodoso ou neurites, mas não referem mudanças na evolução da doença ou sua resposta ao tratamento.…”
Section: Discussionunclassified
“…A i nte ração e ntre a infecção pel o HIV e hanseníase ainda não é inteiramente compreendida. Sabe-se que incidência de hanseníase não é aumentada em pacientes infectados pelo HIV [1][2][3]5,[7][8][9][10] . Nos casos descritos de associação entre hanseníase e aids, não se pode afirmar que a infecção pelo HIV altere a evolução da hanseníase, pelo contrário, a maioria dos relatos demonstra não haver modificações nem clínica, nem imunológica ou histológica e, portanto não haveria necessidade de modificações nos programas de controle da hanseníase 5 .…”
Section: Exame Histopatológicounclassified