Leptospirosis in pregnancy: a case report

Guleria, Sara; Dev, Kapil; Pathania, Kushla

doi:10.18203/2320-1770.ijrcog20223146

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…Clinically, leptospirosis manifests in two phases. The initial phase is characterized by the onset of symptoms, while the second phase, known as the immunogenic phase, is marked by the presence of IgM antibodies [ 4 ]. If leptospirosis in pregnancy is identified and treated promptly, along with thorough monitoring of the fetus, termination of pregnancy is not indicated.…”

Section: Discussionmentioning

confidence: 99%

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Leptospirosis Manifesting as HELLP (Hemolysis, Elevated Liver Enzymes, and Low Platelets) Syndrome: A Rare Case of Leptospirosis During Pregnancy

Patel¹,

Pajai²,

Patel³

et al. 2023

Cureus

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Pregnancy is characterized by a reduced immune response, making pregnant women more susceptible to infections. We present a case of a 24-year-old woman in her second pregnancy who arrived at the hospital at 36 weeks gestation in active labor. The patient had received regular antenatal care including routine prenatal check-ups, screenings, and appropriate vaccinations. She complained of abdominal pain for 5-6 hours, sudden onset of hematuria, and a history of low-grade fever for two days. Physical examination revealed paleness, grade three pedal edema, and elevated blood pressure. Diagnostic tests showed mild anemia, thrombocytopenia, proteinuria, elevated liver enzymes, and kidney dysfunction. The patient was admitted to the labor ward, and a tentative diagnosis of hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome was made. Shortly after arrival, she spontaneously delivered a healthy baby. However, post-delivery, her fever profile indicated the presence of leptospira IgM antibodies, leading to a diagnosis of leptospirosis mimicking HELLP syndrome. Immediate medical treatment resulted in symptom resolution within two weeks and normal biochemical values within a month. Leptospirosis, caused by the gram-negative spirochete bacteria leptospira, is a zoonotic infection rarely observed during pregnancy and can be misdiagnosed due to its atypical presentation. It can mimic other pregnancy-related conditions such as viral hepatitis, obstetric cholestasis, HELLP syndrome, and acute fatty liver of pregnancy. Early detection and treatment are crucial as this disease can have serious consequences for both the mother and fetus. Therefore, leptospirosis should be considered a potential differential diagnosis, particularly in endemic areas.

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Section: Discussionmentioning

confidence: 99%

“…In pregnant women, leptospiral infection can lead to severe maternal morbidity and fetal complications including miscarriage, intrauterine death, and stillbirths during the late trimester [ 3 ]. The case fatality rate among patients with severe illness ranges from 5% to 15% [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Leptospirosis Manifesting as HELLP (Hemolysis, Elevated Liver Enzymes, and Low Platelets) Syndrome: A Rare Case of Leptospirosis During Pregnancy

Patel¹,

Pajai²,

Patel³

et al. 2023

Cureus

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Peripartum Infections: A Position Statement of the Indian Society of Critical Care Medicine

Trikha,

Anand,

Sinha

et al. 2024

Indian Journal of Critical Care Medicine

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A bstract This position statement reviews the evidence and rationale for the management of severe peripartum infections with a special focus on tropical infections and is tailored for resource-limited settings. How to cite this article Samavedam S, Sodhi K, Anand P, Bajwa SJS, Karnad DR, Karanth S, et al . Peripartum Infections: A Position Statement of the Indian Society of Critical Care Medicine. Indian J Crit Care Med 2024;28(S2):S92–S103.

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Leptospirosis in pregnancy: a case report

Cited by 2 publications

References 5 publications

Leptospirosis Manifesting as HELLP (Hemolysis, Elevated Liver Enzymes, and Low Platelets) Syndrome: A Rare Case of Leptospirosis During Pregnancy

Leptospirosis Manifesting as HELLP (Hemolysis, Elevated Liver Enzymes, and Low Platelets) Syndrome: A Rare Case of Leptospirosis During Pregnancy

Peripartum Infections: A Position Statement of the Indian Society of Critical Care Medicine

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