2017
DOI: 10.1002/ccr3.1173
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Leptospirosis presenting as acute acalculous cholecystitis

Abstract: Key Clinical MessageLeptospirosis is the commonest zoonotic infection worldwide but is vastly underreported and extremely heterogeneous in its presentation. Acalculous cholecystitis is an under recognized presentation of acute leptospirosis. In the appropriate clinical context, with a clear exposure history, recognition of this association presents a unifying diagnosis and limits unnecessary surgical interventions.

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Cited by 5 publications
(3 citation statements)
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“…In cases of autoimmune diseases, ischemia due to visceral vasculitis is the implicating causative agent [39]. Endothelial dysfunction and vasculitis are also implicated in cases that AAC is the result of uncommon infections, such as leptospirosis and scrub typhus [40,41]. It is obvious that in a patient with AAC more than one among the aforementioned mechanisms can be present, depending on the patient's underlying disease.…”
Section: Resultsmentioning
confidence: 99%
“…In cases of autoimmune diseases, ischemia due to visceral vasculitis is the implicating causative agent [39]. Endothelial dysfunction and vasculitis are also implicated in cases that AAC is the result of uncommon infections, such as leptospirosis and scrub typhus [40,41]. It is obvious that in a patient with AAC more than one among the aforementioned mechanisms can be present, depending on the patient's underlying disease.…”
Section: Resultsmentioning
confidence: 99%
“…Acalculous cholecystitis is an under-recognized presentation of acute leptospirosis. In the literature, many cases had experienced cholecystectomy with antibiotic treatment in the therapy (8).…”
Section: Discussionmentioning
confidence: 99%
“…After review of the literature, one study concluded that in 6 of 14 reported cases, serovars belonging to L . interrogans were identified as the cause of AAC [ 9 ]. Furthermore, this study describes a case of AAC caused by L .…”
Section: Answer and Discussionmentioning
confidence: 99%