Les complications cardiovasculaires aiguës de la cocaïne. À propos de deux observations

Debien, B.; Clapson, P.; Lambert, E.; Lenoir, B.; Pérez, Jean-Philippe; Pats, B.

doi:10.1016/j.annfar.2005.11.023

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…Notably, anticoagulation with heparin was a common initial treatment across all patients. However, this approach was discontinued in the case reported by Debien et al following the documentation of cerebrovascular hemorrhagic disease in the patient [20].…”

Section: Resultsmentioning

confidence: 99%

Endovascular Treatment of Acute Lower Limb Ischemia Associated with Cocaine Use: A Scoping Review

Muñoz Durán,

Echeverri Isaza,

Hidalgo Oviedo

et al. 2024

Cureus

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The endovascular treatment of acute lower limb ischemia associated with cocaine use is an underexplored topic. This scoping review aims to map existing information and point out potential knowledge gaps for future research. We searched databases with a strategy of terms and keywords (Cocaine, Acute, Lower Limb, and Ischemia) for articles related to acute ischemia in the lower limbs and cocaine use. We established eligibility and exclusion criteria and searched without restrictions on language or date of publication. We obtained five case reports published between 2004 and 2015. Most of the patients were men with an average age of 38 years. Treatments were heterogeneous. Most patients showed improvement after surgical thrombectomy. The sample size and variety of interventions limit the generalizability of the results, so it is necessary to do more studies with robust methodologies to standardize treatments and improve the understanding of the condition.

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Section: Resultsmentioning

confidence: 99%

Endovascular Treatment of Acute Lower Limb Ischemia Associated with Cocaine Use: A Scoping Review

Muñoz Durán,

Echeverri Isaza,

Hidalgo Oviedo

et al. 2024

Cureus

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“…Quelques cas de la littéra-ture rapportent l'implication du cannabis dans la survenue d'infarctus rénaux [11]. La cocaïne est elle aussi clairement identifiée comme facteur de risque cardiovasculaire avec de nombreux cas décrits d'infarctus du myocarde [16][17][18]. Plusieurs observations d'infarctus cérébral [19,20], de dissection aortique [21], d'ischémie mésentérique et rénale [22,23] et d'artériopathie distale [24,25] ont été rapportées.…”

Section: Discussionunclassified

“…La bandelette urinaire retrouvait des traces de sang et une protéinurie à 1 g/L. La numération formule sanguine montrait une hyperleucocytose (17,4 Giga/L) à polynucléaires neutrophiles, l'absence d'anémie, un taux de plaquettes normal. Le bilan hépatique, les ionogrammes sanguin et urinaire, la CRP, l'urémie, la créatininémie, l'électrophorèse des protéines sériques étaient normales.…”

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Infarctus rénal et splénique après consommation massive de cannabis et cocaïne chez un homme jeune

Guen

Gestin

Plat

et al. 2011

Journal des Maladies Vasculaires

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High Serum Tryptase Value in Massive Acute Myocardial Infarction with Ventricular Arrhythmia Exortion in a Cocaine Abuser

Caroselli¹,

Perfetti²,

Bruno

2009

Int J Immunopathol Pharmacol

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A 38-year-old cocaine abuser was admitted to the Emergency Department with a one hour history of precordial chest pain associated with shortness of breath and extreme discomfort. On admission his blood pressure was 90/60 mmHg, the resting 12-lead ECG showed ventricular tachycardia at about 300 beats per minute, and oxygen saturation was 86 percent in room air. After electrical cardioversion, the 12-lead ECG revealed sinusal rhythm and a significative ST segment elevation in leads I, aVL and V1-V6, that was about 0.5 mV in leads I and aVL and more than 1 mV in leads V2, V3 and V4. Laboratory determinations showed elevated creatine-chinase MB (CK-MB) and troponin I. An emergency coronary angiogram was normal. Cocaine use is a major cause of acute myocardial infarction in patients with normal epicardial coronary arteries but the exact mechanism still remains unclear. We hypothesize a non-IgE mediated mast-cell activation, with a direct action played by cocaine, and consequent massive expression of several factors effecting the microcirculatory system, including pro-inflammatory cytokines and chemokines. Our hypothesis is supported by an elevated serum tryptase levels in the patient.

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Les complications cardiovasculaires aiguës de la cocaïne. À propos de deux observations

Cited by 3 publications

References 14 publications

Endovascular Treatment of Acute Lower Limb Ischemia Associated with Cocaine Use: A Scoping Review

Endovascular Treatment of Acute Lower Limb Ischemia Associated with Cocaine Use: A Scoping Review

Infarctus rénal et splénique après consommation massive de cannabis et cocaïne chez un homme jeune

High Serum Tryptase Value in Massive Acute Myocardial Infarction with Ventricular Arrhythmia Exortion in a Cocaine Abuser

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