Les infections du site opératoire en chirurgie orthognathique et leurs facteurs de risque

Barrier, A.C.; Breton, P.; Girard, R.; Dubost, J.; Boulétreau, P.

doi:10.1016/j.stomax.2009.02.003

Cited by 23 publications

(11 citation statements)

References 16 publications

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“…According to this study, the overall rate of severe SSI is acceptable. These results are consistent with other published series in which a single prophylactic dose of AMOXICILLIN CLAVULANIC ACID was used 3 , 15 , 16 . Indeed, Chow et al published the largest series in the literature on that topic and reported a rate of SSI of 7.4%, with a higher prevalence for mandibular location, compared with maxillary site 17 – 19 .…”

Section: Discussionsupporting

confidence: 92%

“…Yet, there is significant heterogeneity regarding the choice of preoperative antibiotic in literature (Table 2 ). Barrier et alnoticed a higher rate of SSI when an antibiotic other than AMOXICILLIN CLAVULANIC ACID was used as prophylaxis 3 . There is evidence suggesting that AMOXICILLIN CLAVULANIC ACID is the best molecule for single dose pre-operative antibioprophylaxis 6 , 7 , 21 – 24 .…”

Section: Discussionmentioning

confidence: 99%

“…Surgical site infections (SSI) following orthognathic surgery occurs in 1.4 to 33.4% of cases. They are a major concern for surgical teams 3 , 4 . Preventive and therapeutic management is not standardized.…”

Section: Introductionmentioning

confidence: 99%

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Severity and long-term complications of surgical site infections after orthognathic surgery: a retrospective study

Cousin

Boulétreau

Giai

et al. 2020

Sci Rep

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Surgical site infections (SSI) occur in 1.4% to 33.4% of cases after orthognathic surgery. This type of complication is a major concern to surgical teams, but there is no consensus for the prevention and treatment of SSI in orthognathic surgery. The purpose of this descriptive study was to evaluate the severity and the consequences of postoperative infections. The charts of all the patients operated on by the orthognathic surgery team between January 2015 and July 2017 were collected. All types of orthognathic procedures (Le Fort I maxillary osteotomy, bilateral sagittal split mandibular osteotomy, and genioplasty) were screened, and patients diagnosed with SSI were included. Demographic data, timing and severity of the infection, as well as long-term complications were recorded. Five hundred and twelve patients were screened. Forty-one patients (8%) presenting with SSI were included. There were 18 men and 23 women. The site of the infection was mandibular for 38 patients (92.7%) and maxillary for 3 patients (7.3%). The average time between surgery and infection was 31.5 days. Twenty-four patients received isolated oral antibiotics for inflammatory cellulitic reaction (58.8%), 15 patients had a localized collection treated by incision and drainage under local anesthesia (36.6%), and 2 patients had an extensive collection requiring surgical drainage under general anesthesia (4.9%). Five patients (12.2%) needed hardware removal for plate loosening, and 2 patients (4.9%) developed chronic osteomyelitis. Infection following orthognathic surgery is easily treated most of the time with no long-term complications. In cases of patients with potential risk factors for severe infection, antibiotics may be given with curative intents.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

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Severity and long-term complications of surgical site infections after orthognathic surgery: a retrospective study

Cousin

Boulétreau

Giai

et al. 2020

Sci Rep

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“…Orthognathic maxillofacial procedures are a common surgery with set of complications [38,39]. Wound infections following orthognathic surgery occurs in 1.4 to 33.4% of patients, what are a major concern for surgical teams [40,41]. With the arms of the ultra-sensitive inflammatory marker independent of age, it increases the confidence to prepare patients for scheduled aseptic surgeries within the maxillofacial skeleton.…”

Section: Discussionmentioning

confidence: 99%

Index of Body Inflammation for Maxillofacial Surgery Purpose-to Make the Soluble Urokinase-Type Plasminogen Activator Receptor Serum Level Independent on Patient Age

2021

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Background: The serum suPAR level is affected in humans by it increases with age. Therefore it makes difficult interpretation and any comparison of age varied groups. The aim of this study is to find simple way to age independent presentation of suPAR serum level for maxillofacial surgery purpose. Methods: In generally healthy patients from 15 to 59 y.o. suPAR level was tested in serum before orthognathic or minor traumatologic procedures. Five ways to make the suPAR serum level assessment independent of age are proposed. Results: One way of making suPAR levels independent of age led to the result with the same statistical distribution as in the raw suPAR serum material and this distribution is the normal. Conclusion: The simple way for suPAR serum level analysis without its dependence on patient age is calculation of the index of body inflammation understood as square root of squared suPAR serum level divided by logarithm of patient age to base 10.

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“…The antibiotic used also varies among studies. Amoxicillin–Clavulanic Acid (Augmentin ® ) is the most effective antibiotic treatment against oral micro-organisms, and few studies showed an increased risk of SSI in patients with penicillin allergy [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Does Penicillin Allergy Increase the Risk of Surgical Site Infection after Orthognathic Surgery? A Multivariate Analysis

Bertin

Meyer

Chatelain

et al. 2022

JCM

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This study aimed to demonstrate an association between the occurrence of surgical site infection (SSI) after orthognathic surgery and penicillin allergy and to assess whether other factors could be associated with the occurrence of SSI. A 10-year monocentric retrospective study was conducted to identify possible risk factors for SSI in orthognathic surgery. Bivariate analyses were performed using Fisher, Student, or Wilcoxon tests and multivariate analyses using logistic regression. Two hundred and sixty-six patients were included, and 3.5% had SSI. Bivariate analyses revealed a significant association between SSI and age at surgery (p = 0.01), penicillin allergy (p = 0.02), and postoperative antibiotic therapy by Clindamycin (Dalacine®) (p = 0.02). Multivariate analyses confirmed the association between the occurrence of SSI and treatment with Clindamycin (Dalacine®) or Clindamycin (Dalacine®) and Metronidazole (Flagyl®) postoperatively (p = 0.04). Antibiotic therapy with Clindamycin (Dalacine®) seems to be associated with a higher rate of SSI, and the mandible was the only site affected by SSI.

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Les infections du site opératoire en chirurgie orthognathique et leurs facteurs de risque

Cited by 23 publications

References 16 publications

Severity and long-term complications of surgical site infections after orthognathic surgery: a retrospective study

Severity and long-term complications of surgical site infections after orthognathic surgery: a retrospective study

Index of Body Inflammation for Maxillofacial Surgery Purpose-to Make the Soluble Urokinase-Type Plasminogen Activator Receptor Serum Level Independent on Patient Age

Does Penicillin Allergy Increase the Risk of Surgical Site Infection after Orthognathic Surgery? A Multivariate Analysis

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