Les manifestations extra-hépatiques de l’hépatite A

Guenifi, Wahiba; Gasmi, Abdelkader; Lacheheb, Abdelmadjid

doi:10.1016/j.revmed.2022.07.007

Cited by 3 publications

(3 citation statements)

References 43 publications

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“…Various microorganisms can cause acute pancreatitis: viruses (hepatotropic virus, coxsackie virus, cytomegalovirus, HIV, herpes virus, etc), fungi (aspergillus), parasites (toxoplasma, cryptosporidium, and ascaris), and bacteria (Mycoplasma, Legionella, Campylobacter jejuni, Salmonella, Chlamydia trachomatis, Brucella, and Leptospira). 4,5 The first descriptions of the association between pancreatitis and leptospirosis date back to the 1950s through clinical observations. 6 Since then, several case series have been published in both adults and children.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Severe Acute Pancreatitis Associated with Weil’s Disease

Guechi

Guenifi

Gasmi

et al. 2023

Middle East J Dig Dis

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Leptospirosis is an emerging zoonosis of worldwide importance. Its distribution is closely linked to hydrometric conditions. It is characterized by a wide clinical range, from the subclinical form, or one with few symptoms; which resolves spontaneously, to the multi-visceral form, known as icterrohemorrhagic disease or Weil’s disease, with a lethal risk. All organs can be affected but with variable frequency. Pancreatic involvement is not well documented. We describe a 45-year-old man with Weil’s disease associated with acute necrotizing pancreatitis. The evolution was favorable but required a three-week stay in the intensive care unit.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Severe Acute Pancreatitis Associated with Weil’s Disease

Guechi

Guenifi

Gasmi

et al. 2023

Middle East J Dig Dis

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“…Currently, due to the increasing incidence of HAV infection among adults, some of the aforementioned complications are frequently detected (14). In a national study, Chen et al (15) recorded a mortality rate of 16.8 per 1000 hospitalizations for HAV infection, with male gender, age greater than 40 years, cirrhosis and long hospitalization predicting worse outcome.…”

Section: Genetic Factors Potentially Involved In Havrelated Autoimmun...mentioning

confidence: 99%

Local and systemic autoimmune manifestations linked to hepatitis A infection

Doulberis,

Papaefthymiou,

Polyzos

et al. 2023

AGEB

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Hepatitis A virus (HAV) represents a global burdening infectious agent causing in the majority of cases a self-limiting acute icteric syndrome, the outcome is related to the hepatic substrate and the potential pre-existing damage, whereas a plethora of extra-hepatic manifestations has also been reported. Despite the absence of post- HAV chronicity it has been associated with an additional burden on existing chronic liver diseases. Moreover, the induced immune response and the antigenic molecular mimicry are considered as triggering factors of autoimmunity with regional and distal impact. Diseases such as autoimmune hepatitis, Guillain-Barré syndrome, rheumatoid arthritis, Still’s syndrome, Henoch-Schönlein purpura, autoimmune hemolytic anemia, antiphospholipid syndrome, systematic lupus erythematosus or cryoglobulinemic vasculitis have been described in patients with HAV infection. Although the exact mechanisms remain unclear, this review aims to accumulate and clarify the pathways related to this linkage.

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Acute hepatitis A complicated by encephalitis: a case report and literature review

Ashour,

Ibrahim,

Muhammed

2024

Egypt Liver Journal

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Background Hepatitis A is the most common cause of acute hepatitis around the globe, especially in developing countries. It often presents with signs and symptoms related to the gastrointestinal system. However, it rarely presents extrahepatic manifestations, which can be more common in adults than in children. Case presentation We report a unique case of hepatitis A presenting with encephalitis that was resolved conservatively. Before attributing the neurological features to hepatitis A, we had to rule out other etiologies with similar presentations. Clinical discussion Many viruses cause encephalitis, such as herpes simplex virus types 1 and 2, varicella zoster virus and enteroviruses. A few cases of hepatitis A complicated by encephalitis have been reported in the literature. In our case, developing a tonic-clonic seizure with no past seizure history demanded more investigations to exclude other etiologies. Ultimately, clinical signs and laboratory investigations led us to consider hepatitis A as the main cause of the patient’s symptoms of encephalitis. Conclusion Hepatitis A virus may present with extrahepatic manifestations more than expected, so more studies and research should be done to increase physicians’ knowledge of these manifestations, make early diagnosis, and administer the effective treatment.

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Les manifestations extra-hépatiques de l’hépatite A

Cited by 3 publications

References 43 publications

Severe Acute Pancreatitis Associated with Weil’s Disease

Severe Acute Pancreatitis Associated with Weil’s Disease

Local and systemic autoimmune manifestations linked to hepatitis A infection

Acute hepatitis A complicated by encephalitis: a case report and literature review

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