Les mélanomes d’apparition précoce (congénitaux, néonataux, du nourrisson) : revue systématique des cas de la littérature

Regnault, M. Masson; Mazereeuw‐Hautier, J.; Fraïtag, Sylvie

doi:10.1016/j.annder.2020.05.001

Cited by 2 publications

(3 citation statements)

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“…Melanoma is very rare in the neonatal period, and there are very few case reports in the literature. The tumor either arises in a giant congenital melanocytic nevus (CMN) or grows from transplacental metastases of the mother's melanoma [38,41]. The estimated risk of developing a melanoma associated with CMN is between 1% and 2% but might be as high as 10% to 15% for large and giant CMN.…”

Section: Melanocytic Lesions In Newbornsmentioning

confidence: 99%

“…The estimated risk of developing a melanoma associated with CMN is between 1% and 2% but might be as high as 10% to 15% for large and giant CMN. Early-onset (congenital, neonatal, and infantile) melanoma usually has a poor prognosis [41]. Melanocytic lesions that arise in association with a congenital melanocytic nevus will be discussed in the next subsection.…”

Section: Melanocytic Lesions In Newbornsmentioning

confidence: 99%

“…However, this feature is not always observed, and its significance is subject to debate. A very high mitotic index, necrosis within the nodule, inflammation, pleomorphism, and high-grade atypia increase the likelihood of a diagnosis of melanoma [41].…”

Section: Melanocytic Lesions Associated With a Congenital Melanocytic Nevusmentioning

confidence: 99%

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Pseudomalignancies in Children: Histological Clues, and Pitfalls to Be Avoided

Menzinger

Fraïtag

2021

Dermatopathology

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The term “pseudomalignancy” covers a large, heterogenous group of diseases characterized by a benign cellular proliferation, hyperplasia, or infiltrate that resembles a true malignancy clinically or histologically. Here, we (i) provide a non-exhaustive review of several inflammatory skin diseases and benign skin proliferations that can mimic a malignant neoplasm in children, (ii) give pathologists some helpful clues to guide their diagnosis, and (iii) highlight pitfalls to be avoided. The observation of clinical–pathological correlations is often important in this situation and can sometimes be the only means (along with careful monitoring of the disease’s clinical course) of reaching a firm diagnosis.

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Section: Melanocytic Lesions In Newbornsmentioning

confidence: 99%

Section: Melanocytic Lesions In Newbornsmentioning

confidence: 99%