Les produits dopants de demain

Rivier, Laurent

doi:10.1051/ata/2000035

Ann Toxicol Anal

2000

DOI: 10.1051/ata/2000035

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Les produits dopants de demain

Laurent Rivier¹

Abstract: RÉSUMÉ Les techniques de dopage chez les sportifs se sont dévelop-pées de façon spectaculaires ces dernières années. Les amateurs de produits ergogènes ont recours à une imagination

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Drugs???for???Increasing???Oxygen???Transport and Their Potential Use in Doping1

Gaudard¹,

Varlet‐Marie

Bressolle

et al. 2003

Sports Medicine

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Blood oxygenation is a fundamental factor in optimising muscular activity. Enhancement of oxygen delivery to tissues is associated with a substantial improvement in athletic performance, particularly in endurance sports. Progress in medical research has led to the identification of new chemicals for the treatment of severe anaemia. Effective and promising molecules have been created and sometimes used for doping purposes. The aim of this review is to present methods, and drugs, known to be (or that might be) used by athletes to increase oxygen transport in an attempt to improve endurance capacity. These methods and drugs include: (i) blood transfusion; (ii) endogenous stimulation of red blood cell production at altitude, or using hypoxic rooms, erythropoietins (EPOs), EPO gene therapy or EPO mimetics; (iii) allosteric effectors of haemoglobin; and (iv) blood substitutes such as modified haemoglobin solutions and perfluorochemicals. Often, new chemicals are used before safety tests have been completed and athletes are taking great health risks. Such new chemicals have also created the need for new instrumental strategies in doping control laboratories, but not all of these chemicals are detectable. Further progress in analytical research is necessary.

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Drugs???for???Increasing???Oxygen???Transport and Their Potential Use in Doping1

Gaudard¹,

Varlet‐Marie

Bressolle

et al. 2003

Sports Medicine

View full text Add to dashboard Cite

show abstract

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Les produits dopants de demain

Abstract: RÉSUMÉ Les techniques de dopage chez les sportifs se sont dévelop-pées de façon spectaculaires ces dernières années. Les amateurs de produits ergogènes ont recours à une imagination

Cited by 1 publication

References 3 publications

Drugs???for???Increasing???Oxygen???Transport and Their Potential Use in Doping1

Drugs???for???Increasing???Oxygen???Transport and Their Potential Use in Doping1

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