Brain Imaging Analysis is a dynamic and exciting field within neuroscience. This study is conducted with two main objectives. First, to develop a classification framework to enhance predictive performance, and second, to conduct a comparative analysis of accuracy versus inference using brain imaging data. The dataset of chess masters and chess novices is utilized to identify neurocognitive differences between the two groups, based on their resting-state functional magnetic resonance imaging data. A network of connections between brain regions is created and analyzed. Standard statistical learning techniques and machine learning models are then applied to distinguish connectivity patterns between the groups. The trade-off between model precision and interpretability is also assessed. Finally, model performance measures, including accuracy, sensitivity, specificity, and AUC, are reported to demonstrate the effectiveness of the model framework.