Introduction: Low back pain is a condition that affects a large number of workers, especially those who perform tasks that require constant physical effort and postures in uncomfortable positions such as in the dairy industry. This type of pain can be caused by various factors, such as repetitive movements, manual manipulation of loads and forced postures during work, which overloads muscles, irritates nerves or wears out joints that can ultimately lead to disability.Objective: To analyze the effect of neuromuscular facilitation on low back pain experienced by workers in dairy factories.Methods: Quasi-experimental study, with longitudinal design and quantitative approach in two study groups (FNP and control) assigned by convenience and selected under inclusion and exclusion criteria. The level of disability associated with low back pain, pain intensity and health-related quality of life were measured, both before and after the intervention.Results: Significant reduction between measurements of the study group compared to the control group in pain intensity (0.04), level of disability associated with low back pain (0.01) and improvement in the level of health-related quality of life . While in the comparison between groups after the intervention, significant differences were obtained in the intensity of pain (0.000), level of disability associated with low back pain (0.000) and improvement in the level of health-related quality of life.Conclusions: FNP in dairy factory workers reduces low back pain, disability and improves quality of life by strengthening the core, stabilizing the spine and reducing the load on the lower back, which benefits performance and prevention of recurrent injuries.