Exposure to mucor mold can lead to mucormycosis, a rare fungal infection with severe consequences, especially in immunocompromised individuals. The year 2020 highlighted the need for orofacial rehabilitation, presenting challenges in cases of maxillary absence. This case report details zygomatic implants, which offer a promising solution by providing stable support even in the absence of significant bone mass due to surgical excision post-COVID-19 mucormycosis. Zygomatic implants outperform traditional grafting techniques. The atrophic or resected jaws can be effectively restored with a single-piece zygomatic implant, which has the lowest rate of postoperative problems, including bone loss, mucositis, peri-implantitis, and screw loosening or fractures. In this case report, four zygomatic implants were placed in the zygomatic bone, and immediate loading was performed. Restoration of patient aesthetics, phonetics, and functional masticatory efficiency were restored.