Lesson of the week Oestrogen and calcium homeostasis in women with hypoparathyroidism

Appraisal of Minerals, Fasting Blood Glucose, and Lipid Parameters in Obese and Nonobese Premenopausal Women

“…The secretion of estrogen hormone increases calcium absorption by stimulating the enzyme alpha-1-hydroxylase present in the kidneys, either directly or indirectly. This is evident because the menopausal decline in estrogen secretions may decrease calcium absorption [ 15 ]. The calcium receptors of parathyroid cells sense the low blood calcium levels in menopausal women.…”

Diagnostic and Therapeutic Aspects of Iatrogenic Hypoparathyroidism

“…Renal calcium losses or their lytogenic effects could be minimized with an adequate dietary approach (hypoproteic, hyposodic diet) 17 combined with thiazide diuretic drugs or cytrate supplementation. Several drugs may interfere with antihypoparathyroidism treatment; Table 3 reports the most relevant interactions 18 • New prospects in hypoparathyroidism treatment might be obtained by the use of human recombinant PTH. So far, however, only few clinical trials have tested the efficacy…”