2018
DOI: 10.1111/jpc.14276
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Lessons learned from a hospital‐wide review of blood stream infections for paediatric central line‐associated blood stream infection prevention

Abstract: Aim Bacteraemia episodes were assessed to calculate a hospital‐wide central line‐associated blood stream infection (CLABSI) rate per 1000 catheter‐days. Secondary objectives were to describe risk factors, microbiology and outcomes of children with CLABSI. Methods A retrospective study was conducted at an Australian tertiary paediatric hospital in children <18 years who had blood culture sampling during the 2‐year period, 2014–2015. All blood culture results were extracted from the hospital's laboratory informa… Show more

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Cited by 6 publications
(6 citation statements)
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“…Despite this, our results underscore the need for improved vascular catheter protocols to prevent hospital-acquired infections across pediatric inpatient settings. 11,33,34 Our results indicating higher rates of HAC for research stays may be explained, at least in part, by clinical differences between research and nonresearch hospitalizations. It is unknown whether patients enrolled in clinical research may be higher acuity, with worse severity or more advanced disease than patients not enrolled in a research study.…”
Section: Discussionmentioning
confidence: 72%
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“…Despite this, our results underscore the need for improved vascular catheter protocols to prevent hospital-acquired infections across pediatric inpatient settings. 11,33,34 Our results indicating higher rates of HAC for research stays may be explained, at least in part, by clinical differences between research and nonresearch hospitalizations. It is unknown whether patients enrolled in clinical research may be higher acuity, with worse severity or more advanced disease than patients not enrolled in a research study.…”
Section: Discussionmentioning
confidence: 72%
“…In addition, there were relatively few events overall resulting in low statistical power and wide CIs for individual HAC. Despite this, our results underscore the need for improved vascular catheter protocols to prevent hospital-acquired infections across pediatric inpatient settings 11,33,34 …”
Section: Discussionmentioning
confidence: 84%
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“…La mediana de la edad en este estudio fue 4 años, diferente a lo encontrado en otras series de pacientes con cáncer donde la edad promedio varía entre 6,5 y 8,3 años 7,8 , probablemente debido a que nuestro estudio incluye otros pacientes como los niños con falla intestinal y atresia esofágica, patologías que se presentan a una edad más temprana. El sexo en algunos estudios es de predominio femenino 7 , mientras que en otros masculino 8,9 , estos últimos como nuestros resultados. En población japonesa que recibió terapia de sello con etanol, se incluyeron niños mayores de 1 año, con una mediana de la edad de 9,4 años y predominio del sexo masculino 10 .…”
Section: Terapia De Sello Terapéuticaunclassified