Lessons Learned from CDC’s Global COVID-19 Early Warning and Response Surveillance System

Ricks, Philip; Njie, Gibril J.; Dawood, Fatimah S.; Blain, Amy; Winstead, Alison; Popoola, Adebola; Jones, Cynthia; Li, Chaoyang; Fuller, James A.; Anantharam, Puneet; Olson, Natalie; Walker, Allison Taylor; Biggerstaff, Matthew; Marston, Barbara J.; Arthur, Ray R.; Bennett, Sarah; Moolenaar, Ronald L.

doi:10.3201/eid2813.212544

Cited by 7 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An increasing body of research is endorsing the transition from event-based surveillance to forecasting or early warning system approaches in surveillance practices [ 34 , 35 ]. Most of the studies are based on virus surveillance by detecting WNV from human samples or by processing mosquitoes that have been collected over several years [ 36 – 39 ].…”

Section: Resultsmentioning

confidence: 99%

Accelerating targeted mosquito control efforts through mobile West Nile virus detection

Varga,

Bueno-Marí,

Risueño Iranzo

et al. 2024

Parasites Vectors

View full text Add to dashboard Cite

Background Different mosquito control strategies have been implemented to mitigate or prevent mosquito-related public health situations. Modern mosquito control largely relies on multiple approaches, including targeted, specific treatments. Given this, it is becoming increasingly important to supplement these activities with rapid and mobile diagnostic capacities for mosquito-borne diseases. We aimed to create and test the applicability of a rapid diagnostic system for West Nile virus that can be used under field conditions. Methods In this pilot study, various types of adult mosquito traps were applied within the regular mosquito monitoring activity framework for mosquito control. Then, the captured specimens were used for the detection of West Nile virus RNA under field conditions with a portable qRT-PCR approach within 3–4 h. Then, positive samples were subjected to confirmatory RT-PCR or NGS sequencing in the laboratory to obtain genome information of the virus. We implemented phylogenetic analysis to characterize circulating strains. Results A total of 356 mosquito individuals representing 7 species were processed in 54 pools, each containing up to 20 individuals. These pools were tested for the presence of West Nile virus, and two pools tested positive, containing specimens from the Culex pipiens and Anopheles atroparvus mosquito species. As a result of subsequent sequencing, we present the complete genome of West Nile virus and Bagaza virus. Conclusions The rapid identification of infected mosquitoes is the most important component of quick response adulticide or larvicide treatments to prevent human cases. The conceptual framework of real-time surveillance can be optimized for other pathogens and situations not only in relation to West Nile virus. We present an early warning system for mosquito-borne diseases and demonstrate its application to aid rapid-response mosquito control actions. Graphical Abstract

show abstract

Section: Resultsmentioning

confidence: 99%

Accelerating targeted mosquito control efforts through mobile West Nile virus detection

Varga,

Bueno-Marí,

Risueño Iranzo

et al. 2024

Parasites Vectors

View full text Add to dashboard Cite

show abstract

“…An increasing body of research is endorsing the transition from event-based surveillance to forecasting or early warning system approaches in surveillance practices [30,31]. Most of the studies are based on virus surveillance by detecting WNV from human samples or by processing mosquitoes that have been collected over several years [32][33][34][35].…”

Section: Resultsmentioning

confidence: 99%

Accelerating targeted mosquito control efforts through mobile West Nile virus detection

Varga,

Bueno-Marí,

Iranzo

et al. 2023

Preprint

View full text Add to dashboard Cite

Background Different mosquito control strategies have been implemented to mitigate or prevent mosquito-related public health situations. Modern mosquito control largely relies on multiple approaches, including targeted, specific treatments. Given all this, it is becoming increasingly important to supplement these activities with rapid and mobile diagnostic capacities for mosquito-borne diseases. We aimed to create and test the applicability of a rapid diagnostic system for West Nile virus that can be used under field conditions. Methods In this pilot study various types of adult mosquito traps were applied within the regular mosquito monitoring activity framework for mosquito control. Then the captured specimens were used for the detection of West Nile virus RNA under field conditions with a portable qRT-PCR approach within 3–4 hours. Then positive samples were subjected to NGS sequencing in the laboratory to obtain genome information of the virus. We implemented phylogenetic analysis to characterize circulating strains. Results 54 mosquito pools were processed and tested for the presence of West Nile virus, of which 2 pools were positive, containing specimens of Culex pipiens and Anopheles atroparvus mosquito species. As a result of subsequent sequencing, we present the complete genome of West Nile virus. Conclusion The rapid identification of infected mosquitoes is the most important component of quick response adulticide or larvicide treatments to prevent human cases. The conceptual framework of real-time surveillance can be optimized for other pathogens and situations not only in relation to West Nile virus. We present an early warning system for mosquito-borne diseases and demonstrate its application to aid rapid-response mosquito control actions.

show abstract

“…Big data surveillance monitoring, or observational monitoring not guided by hypotheses, was important early in the pandemic to track where cases were. However, its utility has decreased (Ricks et al, 2022). Targeted monitoring data that addressed questions such as effectiveness of social distancing, public closures, and self-imposed or mandated quarantines were needed to inform policy and individual decision-making.…”

Section: The Challenges and Opportunities Of Using Big Data In A Nove...mentioning

confidence: 99%

Lessons for conservation from the mistakes of the COVID‐19 pandemic: The promise and peril of big data and new communication modalities

Golding,

Chmura

2024

Conservat Sci and Prac

View full text Add to dashboard Cite

New datasets and information infrastructure are revolutionizing how societies respond to environmental crises, while creating novel challenges. Conservation biology can learn from other fields that have confronted crises while navigating changes in the scientific process. The COVID‐19 pandemic offers one such opportunity. We identify lessons from the use of big data and the sharing of preliminary scientific information in an increasingly “networked” communication system during the pandemic. Although big data were central to early pandemic responses, acquisition and sharing of big data alone were insufficient to produce knowledge for effective crisis response. Some shortcomings could be addressed by validating and automating processing of big data. Preliminary scientific information was widely available and shared through a broad communication infrastructure during the pandemic, contributing to widespread misinformation. Diverse actions connecting information producers and consumers could help mitigate misinformation risk. By examining pandemic lessons, conservation biologists may be better equipped to handle conservation crises.

show abstract

Lessons Learned from CDC’s Global COVID-19 Early Warning and Response Surveillance System

Cited by 7 publications

References 6 publications

Accelerating targeted mosquito control efforts through mobile West Nile virus detection

Accelerating targeted mosquito control efforts through mobile West Nile virus detection

Accelerating targeted mosquito control efforts through mobile West Nile virus detection

Lessons for conservation from the mistakes of the COVID‐19 pandemic: The promise and peril of big data and new communication modalities

Contact Info

Product

Resources

About