Yitong Basin is located in subfrigid zone, and it has a good prospect to use geothermal clean heating. The evaluation of economic efficiency for heating with enhanced geothermal system (EGS) is indispensable. A simplified single‐fracture hydrothermal coupling model with laboratory test is developed in the EGS project to calculate temperature and pressure based on Yitong Basin data. The effects of four factors (K, q, D, and T) on heat production and reservoir characteristics are discussed. The parameters and results of H‐T coupling were applied to economic analysis for heating with EGS from private and social perspectives considering costs and revenues. The results indicate that the combination of laboratory tests (rock physical properties) makes the numerical simulation results more suitable for the study area. The production temperature and heating power will decrease with continuous injection of cold water, and the injection pressure and flow impedance will increase due to the increase in μ/ρ. Four factors (K, q, D, and T) will affect difficulty of fluid injection and reservoir thermal breakthrough, and the high injection rate q may trigger secondary fracturing of reservoir. Heating with EGS in single‐fracture model was uneconomical due to expensive drilling costs. However, heating with EGS can be considered from social perspective based on environment, which can provide advice for decision‐making of the government and business.