The advent of Industry 4.0 technologies, encompassing the Internet of Things (IoT), Big data analytics, artificial intelligence (AI), blockchain, location-based services, and virtual and augmented (VR/AR) reality systems, has revolutionized the tourism landscape, automating production and service delivery. As the momentum of Industry 4.0 propels us toward the tourism-specific concept of Tourism 4.0, questions arise about the ability of humans to keep pace with the rapid technological advancements and ensure these innovations genuinely benefit society. The ongoing debate prompts a call for humanizing Industry 4.0, echoed in the emerging concept of Industry 5.0, advocating for more responsible and humane technology approaches. Concurrently, voices championing Tourism 5.0 emphasize the need to align technology with diverse human tourism needs and enhance accessibility for a more inclusive and meaningful travel experience. Through this chapter, we endeavor to establish Tourist 5.0 as a holistic alternative to the prevailing concept of digital accessibility practices within the typically limited and task-focused tourism sector. This chapter critically examines the evolution from Industry 4.0 to Industry 5.0, drawing parallels with Tourism 4.0 and Tourism 5.0. The central focus of this chapter is placed on the imperative of technological accessibility, exploring how it takes precedence in the latest technological developments and contributes to the creation of more inclusive and fulfilling tourism experiences.