Letter by Nakagawa, <i>et al</i>. Regarding Article, "Simple Score to Predict Treatment Response to Low-Dose Tolvaptan in Patients with Heart Failure"

Reply to Letter Regarding Article, "Simple Score to Predict Treatment Response to Low-Dose Tolvaptan in Patients with Heart Failure"

“…We appreciate the comments provided to us in the letter, and we thank the editors for the opportunity to respond to expand the discussion of our work. We would like to address the concerns about the findings of our study raised by Nakagawa, et al 1) Their first suggested problem was the definition of the responder of tolvaptan. In our study, not urine volume, but required dose-escalation of tolvaptan was used to define a non-responder of tolvaptan.…”