“…In their letter to the editor, Qiu and Du 2 appropriately noted that the results of our meta-analysis could be limited by the small number of events included in the analysis in assessing the composite outcome of interest (all-cause mortality/hospitalization). They argued that the analysis should have included the data from trials that reported the outcomes of all-cause death or hospitalization individually and should not be limited to the 4 randomized controlled trials that reported this composite outcome.…”