Letter From Mr. Bateman, of Islington.

The mechanism of transcription termination by RNA poiymerase I

“…Several reports have shown that an upstream poll terminator can have a stimulatory effect on a downstream poll promoter by preventing promoter occlusion (Bateman and Paule, 1988;Henderson ef ai., 1989;McStay and Reeder, 1990a). In X. iaevis it has also been shown that the T3 terminator can positively affect the nearby gene promoter by a different mechanism which probably involves direct communication between the two elements (McStay and Reeder, 1986;.…”

“…In most eukaryotes these genes are present in long tandem arrays of head-tO'tail repeats. It is well established that if polymerase from one repeat unit is allowed to transcribe over the promoter of the adjacent downstream repeat, the downstream promoter will be occluded and shut off (Bateman and Paule, 1988;Henderson et ai. 1989: McStay and.…”

Reforming Medical Manslaughter, the Scottish Way?

“…93 Rather, 'outrage' is manifested in response to acts that demonstrate that a doctor was indifferent to the welfare of their patient, that they willingly exposed their patient to an unjustifiable risk of harm and, therefore, were reckless. 94 The reference to 'disregard' in Bateman 95 is indicative of behaviour which to 'lay persons' and is synonymous with 'recklessness', yet this direction fails to truly clarify the type of behaviour which ought to attract criminal sanctions. 96 In setting the threshold for criminal punishment at 'recklessness so high as to involve an indifference to the consequences', culpable homicide may thus be considered a neater articulation of Bateman, 97 with the requirement of 'utter disregard' reinforcing the importance of a blameworthy mind to any criminal conviction.…”

“…When the need for 'total indifference' is taken with the requirement of a 'disregard for the safety of the public,' 205 the use of the conjunctive 'and' is indicative of a higher degree of disregard than that stipulated in Bateman, where Lord Hewart CJ stressed the need for 'such disregard for the life and safety of others.' 206 Yet as with Bateman, 207 it remains questionable whether it is possible to draw any meaningful distinction between a 'complete disregard' 208 and a mere 'disregard'. If the term is interpreted as requiring a defendant to be aware of the dangers within their conduct, whether they disregarded a risk is surely binary.…”

Difficult Psychiatric Consultations

“…This process involves the ability to interpret behavior as meaningful and as based on the mental states and psychological makeup of both the self and others, such as desires, needs, beliefs, reasons, and feelings. Mentalization-based treatment (MBT) is becoming widely recognized as helpful for patients with personality disorders in both adolescents (Rossouw and Fonagy 2012) and adults (Bateman andFonagy 2008, 2009). It is accepted that persons with a history of being securely attached have good mentalizing abilities, while a person who grew insecurely attached has difficulty mentalizing and makes use of maladaptive defense mechanisms.…”