Leucemia viral felina: revisão

Alves, Maria Cecília Rodrigues; Conti, Laura; Júnior, Paulo Sérgio Cruz de Andrade; Donatele, Dirlei Molinari

doi:10.22256/pubvet.v9n2.86-100

Cited by 15 publications

(22 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…False positive animals for FeLV, have already been reported in studies that compared the ALERE immunochromatographic tests, which was used in this study and the SNAP®, with the SNAP® showing a greater number of false positive results and the ALERE test showed greater specificity (Westman et al, 2016a;Medeiros et al, 2019). Development, v. 9, n. 7, e205974039, 2020 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i7.4039 Also according to Alves et al (2015), it is believed that animals negatives in the rapid test and positives in the detection of FeLV by PCR possibly will not be disseminators of the agent and will hardly develop the disease due to the low circulating viral load.…”

Section: It Is Observed Inmentioning

confidence: 98%

“…For FeLV, the immunochromatography searches for the antigen, which normally circulates in the blood for two or three weeks after the feline was exposed to the agent (Alves et al, 2015). More recent methods of diagnosing FeLV, such as PCR can find the genetic material of the agent in the host's DNA (Arjona et al, 2007;Westman et al, 2016a).…”

Section: It Is Observed Inmentioning

confidence: 99%

“…If the cat has a regressive infection, the viremia will become smaller and the immunochromatographic test will be unable to detect, despite the fact that FeLV is positive (Alves et al, 2015), what happened to 37 animals of that type study, consisting of false negative results. This usually occurs because the animal organism eliminates the virus from the circulation, but not before it inserts its genetic material into predilection cells, such as bone marrow (Arjona et al, 2007;Figueiredo;Araújo-Júnior, 2011;Spada et al, 2018).…”

Section: It Is Observed Inmentioning

confidence: 99%

“…Since the rapid test is able to detect only the antigen, there is no interference from maternal antigens circulating in the blood of the felines or vaccines, and there is no minimum age to test the puppies (Alves et al, 2015).…”

Section: It Is Observed Inmentioning

confidence: 99%

“…Although exist some anti-retroviral drugs that work in a more specific way, there is a need for more studies of the real benefits of these drugs (Alves et al, 2015). The main test routinely used by veterinarians is the immunochromatographic test.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Comparison between immunochromatographic tests and polymerase chain reaction for FIV and FeLV diagnosis

Campbell¹,

Lemos²,

Dutra

et al. 2020

RSD

View full text Add to dashboard Cite

The retroviruses responsible for feline immunodeficiency and feline leukemia are spread around the world, affecting a large number of animals. These diseases are lifelong and manifest when the cat is immunosuppressed, bringing numerous consequences to their health. The correct and early diagnosis helps in the management of both infected and uninfected animals in order to extend the life of these felines with quality. The present work aims to compare two different tests for the diagnosis of these diseases, in order to discuss the reason for the discrepancy between the results, to demonstrate the positive and negative points of each one and to help the clinician to choose the best method to be used in each situation. The immunochromatographic test and PCR was performed in 66 animals living in the city of Mineiros, Goiás, Brazil. Among these, eight animals were positives in the immunochromatographic test and five in the PCR test for diagnosis of FIV. For FeLV, there were only one positive feline on immunochromatography and 38 positives on PCR. With this result, the conclusion is that both tests have their limitations and one should consider the pathogenesis of the agent in order perform the test correctly or associate them.

show abstract

Section: It Is Observed Inmentioning

confidence: 98%

Section: It Is Observed Inmentioning

confidence: 99%

Section: It Is Observed Inmentioning

confidence: 99%

Section: It Is Observed Inmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Comparison between immunochromatographic tests and polymerase chain reaction for FIV and FeLV diagnosis

Campbell¹,

Lemos²,

Dutra

et al. 2020

RSD

View full text Add to dashboard Cite

show abstract

Detection of the Presence of Feline Viral Leukemia Virus (FeLV) Using the PCR Technique

Martins¹,

Knackfuss²,

Voight³

et al. 2022

JASR

View full text Add to dashboard Cite

The present study aimed to evaluate, using the Polymerase Chain Reaction (PCR) technique, the detection of the virus that causes Feline Viral Leukemia (FeLV) in blood samples from a group of 12 unvaccinated cats that lived together. In order to control the technique, 2 more animals were used that already had a positive result for FeLV in the SNAP FIV/FeLV rapid test (Combo IDEXX). Among the group of 12 cats, there were 4 males and 8 females with ages ranging from 7 months to 4 years of age, which were rescued from the wild in the municipality of São Gonçalo, Rio de Janeiro at different times. FeLV is a disease caused by a virus belonging to the Retroviridae family and its main route of elimination is through the saliva of contaminated felines. It has a high incidence in the clinical routine affecting domestic felines, being the most susceptible those that are free-living. Positive animals may be asymptomatic or show clinical signs such as the anorexia, apathy, anemia, stomatitis and even the appearance of lymphomas. For the spread of this disease, direct contact with a positive feline is necessary, which can be through the sharing of feeders and drinkers or through fights and licks, since the virus does not resist outside the host and is easily eliminated by cleaning products. . This disease has different forms of infection, including the abortive infection, in which the virus is eliminated by the immune system, the regressive form in which the virus spreads to monocytes and lymphocytes, and the progressive form where viral replication is intense, spread to bone marrow, epithelial and glandular tissues. PCR is able to detect the presence of the virus even in the regressive form of the infection, whereas rapid serological methods cannot. In view of this, it is important to carry out this routine diagnostic method for FeLV, since there are positive animals that are asymptomatic. The realization of this study allowed a reliable diagnosis from PCR, in which of these animals, the 2 animals already positive confirmed to be also in PCR, while the group of 12 that lived together had a negative result. Because it is considered one of the most serious diseases that affect cats and that has no cure, diagnosis is very important to prevent the spread of the disease to other healthy cats.

show abstract

Imunodeficiência viral felina: Relato de caso

Carvalho¹,

Amorim²,

Sá³

et al. 2019

Pubvet

View full text Add to dashboard Cite

Resumo. O objetivo do trabalho é mostrar o desempenho do tratamento paliativo da Imunodeficiência Viral Felina -FIV e sua capacidade de recuperar a qualidade de vida dos animais que foram acometidos pela doença. Desta forma foi realizado um relato de caso de um animal atendido no Hospital Veterinário Universitário -HVU de Teresina -PI, um gato, macho, SRD, de 2 anos de idade, pesando 6 kg. O proprietário relatou que há uma semana o abdômen do animal aumentou de tamanho, o mesmo apresentava normodipsia, normofagia, alimentação a base de ração e frango, não soube informar se o animal estava urinando ou como estava as fezes, vermifugação atrasada, vacinado contra raiva, não castrado, com acesso à rua, convive com um jaboti, dois cães, três gatos filhotes todos saudáveis. No dia 03 de setembro de 2017 o animal retornou ao HVU -UFPI, com o resultado de todos os exames, tendo o animal reagido positivo no teste para detecção de anticorpo "FIV". Assim como outras doenças causadas por retrovírus, a imunodeficiência felina não tem cura, por isso é essencial que se dedique na prevenção desta enfermidade. Animais infectados devem ter cuidados redobrados para que os mesmos continuem vivendo normalmente, com qualidade de vida e bem-estar. A doença não deve ser tratada como um atestado de óbito, devendo lembrar sempre que mesmo não existindo cura, o tratamento paliativo é uma alternativa para zelar a vida desses animais.

show abstract

Leucemia viral felina: revisão

Cited by 15 publications

References 14 publications

Comparison between immunochromatographic tests and polymerase chain reaction for FIV and FeLV diagnosis

Comparison between immunochromatographic tests and polymerase chain reaction for FIV and FeLV diagnosis

Detection of the Presence of Feline Viral Leukemia Virus (FeLV) Using the PCR Technique

Imunodeficiência viral felina: Relato de caso

Contact Info

Product

Resources

About