Leucograma e metabolismo oxidativo de neutrófilos em cabras da raça Saanen nos períodos de gestação, parto e pós-parto

Abstract

RESUMO.-O presente estudo teve como objetivo a avaliação do leucograma e do metabolismo oxidativo de neutrófilos em fêmeas caprinas da raça Saanen, nos períodos The purpose of this study was to evaluate the leukocyte count and the oxidative metabolism of neutrophil in Saanen goats during periods of pregnancy, parturition and postpartum. Were used 20 Saanen goats, clinically healthy and serologically negative for caprine arthritis encephalitis virus (CAEV). Blood samples were collected by jugular venipuncture 49 (M1), 42 (M2), 35 (M3), 28 (M4), 21 (M5), 14 (M6), seven (M7), three (M8) days before the parturition, on the day of birth (M9), three (M10) and seven (M11) days postpartum, for the leukocyte count, and serum for cortisol, estradiol and progesterone determination. From 28 days (M4) before parturition until seven days postpartum (M11) blood samples were collected for evaluation of oxidative metabolism of neutrophils by the nitroblue tetrazolium reduction test (NBT). The results showed that at parturition day there were an increase in cortisol and estradiol levels and a decrease in progesterone serum, neutrophilic leukocytosis and left shift slight, decrease of lymphocytes, increase in the neutrophil: lymphocyte, eosinopenia, monocytosis and basophilia. There was a neutrophilic leukocytosis and an increase in the neutrophil: lymphocyte on the seventh day postpartum. There were not significant alterations in oxidative metabolism of neutrophils during pregnancy, parturition and postpartum. It was concluded that parturition causes an elevation in cortisol and estradiol levels and a decrease in progesterone serum determining a neutrophilic leukocytosis and left shift slight, with a reduction of lymphocytes, increase in the neutrophil:lymphocyte, eosinopenia, monocytosis and basophilia. Neutrophilic leukocytosis, increase in the neutrophil: lymphocyte and fibrinogen are detected on the seventh day postpartum. Pregnancy, parturition and the postpartum do not change the oxidative metabolism of neutrophils evaluated by NBT reduction test. de gestação, parto e pós-parto. Amostras de sangue foram colhidas de 20 fêmeas nulíparas da raça Saanen, clinicamente sadias por venipunção jugular aos 49 (M1), 42 (M2),

Hematological, parasitological and biochemical parameters in sheep during the peripartum period

“…Segmented neutrophils act as a first line of defense against infection. Many researchers have investigated the activity of these leukocytes close to delivery (Guidry et al, 1976;Fonteque et al, 2013). The level of segmented neutrophils increased as delivery approached, peaking on day 0 (delivery), with a gradual decrease afterward.…”

Influence of lambing on the metabolic profile, neutrophil function and IgG levels in Lacaune sheep

“…Both the primiparous and the multiparous ewes exhibited lower MOB in the early moments of the postpartum period. A lower percentage of MOB soon after delivery was also detected by Fonteque et al (2013). The assessment of the MOB indicates the presence of blood neutrophils.…”

Avaliação Do Período Periparto Por Parâmetros Clínicos E Hematológicos Em Cabras Leiteiras

“…A elevação do fibrinogênio imediatamente após o parto pode ser devido a lesão causada durante o parto ou mesmo as alterações ocorridas no processo de expulsão da placenta, conforme relatado por Fonteque et al (7) .…”

“…Adicionalmente, outros fatores como a idade, as condições ambientais, o regime de manejo, a fase reprodutiva e a lactação também podem ocasionar variações fisiológicas nesses animais (4,5) , comprometendo assim a produtividade. A gestação, o parto e a lactação são considerados períodos de estresse físico e metabólico para os animais (6,7) , e durante a gestação ocorrem alterações no sistema hematopoético materno, a fim de satisfazer as necessidades do desenvolvimento do feto e da mãe (7) . Sendo assim, o periparto é considerado uma fase crítica, uma vez que a maioria dos distúrbios metabólicos ocorre durante este período, no qual o crescimento e expulsão do feto junto a produção de leite impõem enormes demandas fisiológicas (8,9) .…”