Leukaemia and lymphoma risks derived from solvents

Brandt, L.

doi:10.1007/bf02934516

Cited by 7 publications

References 46 publications

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A case-control study of cancer mortality at a transformer-assembly facility

Greenland

Salvan

Wegman

et al. 1994

Int. Arch Occup Environ Heath

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To address earlier reports of excess cancer mortality associated with employment at a large transformer manufacturing plant, each plant operation was rated for seven exposures: Pyranol (a mixture of polychlorinated biphenyls and trichlorobenzene), trichloroethylene, benzene, mixed solvents, asbestos, synthetic resins, and machining fluids. Site-specific cancer deaths among active or retired employees were cases; controls were selected from deaths (primarily cardiovascular deaths) presumed to be unassociated with any of the study exposures. Using job records, we then computed person-years of exposure for each subject. All subjects were white males. The only unequivocal association was that of resin systems with lung cancer (odds ratio = 2.2 at 16.6 years of exposure, P = 0.001, in a multiple logistic regression including asbestos, age, year of death, and year of hire). Certain other odds ratios appeared larger, but no other association was so robust and remained as distinct after considering the multiplicity of comparisons. Study power was very limited for most associations, and several biases may have affected our results. Nevertheless, further investigation of synthetic resin systems of the type used in the study plant appears warranted.

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A case-control study of cancer mortality at a transformer-assembly facility

Greenland

Salvan

Wegman

et al. 1994

Int. Arch Occup Environ Heath

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Leukocytic Disorders

Hutchison¹,

Schexneider²

2011

Henry's Clinical Diagnosis and Management by Laboratory Methods

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non-Hodgkin's lymphoma and occupation in Sweden: a registry based analysis.

Linet

Malker

Mclaughlin

et al. 1993

Occupational and Environmental Medicine

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Incidence of non-Hodgkin's lymphoma in different employment categories was evaluated from the Swedish Cancer-Environment Registry, which links cancer incidence during 1961 to 1979 with occupational information from the 1960 census. New associations were found for men employed in shoemaking and shoe repair, porcelain and earthenware industries, education, and other white collar occupations. Several findings supported associations found in other countries, including excesses among woodworkers, -furniture makers, electric power plant workers, farmers, dairy workers, lorry drivers, and other land transport workers. Risks were not increased among chemists, chemical or rubber manufacturing workers, or petrochemical refinery workers. Caution must be used in drawing causal inferences from these linked registry data because information on exposure and duration of employment is not available. Nevertheless, this study has suggested new clues to possible occupational determinants of non-Hodgkin's lymphoma. (British Journal of Industrial Medicine 1993;50:79-84) During the past few decades, incidence of nonHodgkin's lymphoma has been increasing in many countries including Sweden, particularly among the elderly."q Although some of this increase may reflect diagnostic improvements, environmental and occupational factors have also been implicated.5 The relation of occupational exposures to non-Hodgkin's lymphoma has not been extensively evaluated,

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Leukaemia and lymphoma risks derived from solvents

Cited by 7 publications

References 46 publications

A case-control study of cancer mortality at a transformer-assembly facility

A case-control study of cancer mortality at a transformer-assembly facility

Leukocytic Disorders

non-Hodgkin's lymphoma and occupation in Sweden: a registry based analysis.

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