“…EP/LEM is known to increase the number of circulating leukocytes (MITCHELL and KAMPSCHMIDT, 1985). Intravenous injection of endotoxin is followed by a rapid decrease in the leukocyte number.…”
Section: Discussionmentioning
confidence: 99%
“…The described changes have primarily been attributed to the mediators called endogenous pyrogen (EP) and leukocytic endogenous mediator (LEM) (DINARELLO, 1984;MITCHELL and KAMPSCHMIDT, 1985). The role of EP/LEM is however still a matter for u.s.…”
“…EP/LEM is known to increase the number of circulating leukocytes (MITCHELL and KAMPSCHMIDT, 1985). Intravenous injection of endotoxin is followed by a rapid decrease in the leukocyte number.…”
Section: Discussionmentioning
confidence: 99%
“…The described changes have primarily been attributed to the mediators called endogenous pyrogen (EP) and leukocytic endogenous mediator (LEM) (DINARELLO, 1984;MITCHELL and KAMPSCHMIDT, 1985). The role of EP/LEM is however still a matter for u.s.…”
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