Leukotriene inhibitors for bronchiolitis in infants and young children

Epidemiology, clinical characteristics, laboratory findings and severity of respiratory syncytial virus acute lower respiratory infection in Malaysian children, 2008–2013

“…Montelukast and systemic corticosteroid usage were common in our institution because some patients had persistent wheezing, precluding discharge although their benefits in RSV ALRI are questionable …”

Change in viral bronchiolitis management in primary care in the UK after the publication of NICE guideline

“…However, it is worrying 34% of respondents prescribe a medication because they believe there is good evidence it helps the infant. There is clear evidence from systematic reviews, noted in the NICE guideline, that medications including bronchodilators,5 corticosteroids,6 leukotriene receptor antagonists7 and antibiotics8 are not efficacious. More widespread use of, and familiarity with, the NICE guideline could potentially improve GPs’ knowledge and thus clinical practice in this area.…”

The modified respiratory index score (RIS) guides resource allocation in acute bronchiolitis

“…Bronchiolitis is one of the most common diseases in young children. Previous clinical trials have demonstrated that most interventions are not effective in treating bronchiolitis . The main tenet of management remains supportive.…”

“…Previous clinical trials have demonstrated that most interventions are not effective in treating bronchiolitis. [19][20][21][22] The main tenet of management remains supportive. In the evaluation and treatment of bronchiolitis, there is marked practice variation, as reflected in the differential admission rates and treatment The Modified RIS in Acute Bronchiolitis decisions.…”